What are the responsibilities and job description for the Senior Scientist/Associate Director, Clinical Biomarkers position at Nurix Therapeutics?
The Position
In order to make an application, simply read through the following job description and make sure to attach relevant documents.
The Senior Scientist / Associate Director of Clinical Biomarkers will play a pivotal role in advancing biomarker strategies to support the clinical development of Nurix’s innovative therapies targeting protein homeostasis. As a leader in the Clinical Biomarkers team, the successful candidate will collaborate across research, clinical development, and external partnerships to drive the biomarker strategy for early phase clinical trials. This role involves leading the design, execution, and interpretation of biomarker assays. These efforts will contribute to patient selection, pharmacodynamic assessments, and the elucidation of drug mechanisms of action.
Specific responsibilities include :
- Lead the development, validation, and execution of clinical biomarker strategies to inform patient stratification, response prediction, and resistance mechanisms across Nurix’s clinical programs.
- Leverage deep expertise in cell and tumor biology, molecular biology, inflammation and immuno-oncology to design and interpret both preclinical and clinical biomarker studies.
- Oversee biomarker assay development, including assay qualification and execution on diverse platforms, to support pharmacodynamic and predictive biomarker analysis in clinical trials.
- Lead the evaluation and implementation of novel biomarker assays in both nonclinical models and patient-derived samples, ensuring alignment with clinical trial objectives.
- Collaborate closely with multidisciplinary teams, including research scientists, clinical development, external collaborators, and contract research organizations (CROs), to ensure seamless integration of biomarker data into clinical development plans.
- Provide scientific and strategic input into clinical trial designs, ensuring biomarker data are effectively utilized to guide therapeutic decisions and optimize patient outcomes.
- Mentor and manage junior scientists, fostering a collaborative and innovative research environment.
Education and Skills Requirements :
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