What are the responsibilities and job description for the Research Associate/Senior Research Associate, Analytical Development (Viral Vector) - Contractor position at Obsidian Therapeutics?
Research Associate / Senior Research Associate, Analytical Development (Viral Vector) - Contractor
Bedford, MA
About Us…
Obsidian Therapeutics is expanding the reach of TIL therapy. We are pioneering engineered tumor infiltrating lymphocyte (TIL) therapies to deliver transformative outcomes for patients suffering from solid tumor malignancies. Obsidian’s programs apply our cytoDRiVE® platform technology to express regulated therapeutic proteins to enhance anti-tumor activity. We are investigating OBX-115 and enrolling patients in an ongoing multicenter clinical trial in advanced melanoma and non-small cell lung cancer ( Agni-01 ).
We’re proud of our diverse talented team and committed to cultivating an environment where each person feels a strong sense of belonging and is supported to continuously learn and contribute their best work. Our research team is based in the heart of Cambridge, MA, and our Technical Development, Manufacturing & Quality team is based in our facility in Bedford, MA. Obsidianites enjoy a highly collaborative culture, competitive salary and benefits, and potential for ownership through stock options.
In April 2024, we announced closure of an oversubscribed $160.5 million Series C financing with a top-tier syndicate of life science investors to advance Obsidian’s lead program in its ongoing trials.
Our Opportunity…
We’re looking for a highly motivated scientist to join our analytical development Viral Vector team. You will focus on characterizing gamma retroviral vectors in support of clinical development of cell therapy products. Based in our Bedford, MA location, you’ll support critical studies and experiments to advance Obsidian OBX-115 product understanding. You’ll work with subject matter experts across different functional groups, affording the potential for significant learning and career development. This position is part of the Viral Vector Analytical Development team which supports assay development and qualification in addition to vector characterization and testing for internally produced and externally produced lots.
As a member of our Technical Operations team you'll be a vital part of a highly collaborative team working to achieve the Obsidian’s vision by translating innovative science into medical breakthroughs for patients, starting with our lead program OBX-115, a novel engineered tumor-infiltrating lymphocyte (TIL) therapy.
This is a unique opportunity to be a contributor in a well-funded clinical company with blue chip investors, field-leading advisors, best-in-class partners, and an experienced team. You'll help us build a dynamic, innovative, passionate, collaborative, and successful organization focused on delivering transformative therapies in areas of greatest clinical need.
You will...
- Collaborate with team leaders to characterize cell-based products and viral vectors.
- Execute carefully planned experiments, troubleshoot assays, discuss data, and communicate findings / present results at internal meetings.
- Apply your technical and analytical skills needed to support viral vector product characterization, including but not limited to molecular biology tools like ddPCR and ELISA.
- Author and review technical methods and reports.
- Maintain timely and robust record keeping in ELN.
- Support lab functions including but not limited to maintaining reagent supplies, restocking consumables, lab organization, etc.
- Make intellectual and technical contributions to projects.
- Maintain a safe work environment in accordance with policies / procedures / regulations.
You bring...
Core Qualifications
Bonus Qualifications
J ob level (Research Associate / Senior Research Associate) will be determined based on overall skillset and experience according to Obsidian’s job level criteria.
Please no agency solicitation at this time. Thank you for respecting this request.
Obsidian is proud to be an equal opportunity employer, cultivating a welcoming and diverse environment. All applicants will receive consideration for employment without regard to race, color, religion, gender, gender identity or expression, sexual orientation, national origin, genetics, disability, age, veteran status or any other applicable legally protected characteristics.