What are the responsibilities and job description for the Scientist I, BioA / DMPK / BioMarker position at PepGen?
PepGen is seeking a highly motivated and talented Scientist to join our Bioanalytical and DMPK team. In this hands-on laboratory position, the successful candidate will be responsible for designing, developing, and validating bioanalytical assays for preclinical and clinical studies. The individual will also perform DMPK experiments to support drug discovery and development, requiring strong HPLC separation skill and experience with Thermo QE . The focus of the role is relatively open depending on the candidate's experience, from discovery to clinical bioanalytical support.
About the Team
This Bioanalytics, DMPK team at PepGen will support all DMPK related activities, such as bioanalytics, biotransformation, PK / TK analysis, DDI etc, as well biomarker support.
Responsibilities
- Design, develop, and validate bioanalytical assays for quantifying small molecules, peptides, oligonucleotides and proteins in various biological matrices using LC-MS / MS, ELISA, and other relevant techniques
- Develop and optimize bioanalytical methods in house and assist for CRO method development and trouble shooting
- Assist in PK calculation and analysis
- Design human ADME study to identify and characterize drug metabolites / catabolites
- Provide bioanalytical support for discovery and development research needs independently
- Analyze and interpret data and prepare reports. Present data and findings in internal and external meetings.
- Collaborate with other team members cross functionally to ensure the timely delivery of high-quality data
- Maintain laboratory equipment and supplies and troubleshoot any issues.
- Adhere to laboratory safety protocols and maintain accurate laboratory notebooks and records
Qualifications
Note : This is an on-site role. The candidate will need to be on-site five days / week.
About PepGen
PepGen Inc. is a clinical-stage biotechnology companyadvancing the next-generation of oligonucleotide therapies with the goal of transforming the treatment of severe neuromuscular and neurological diseases. PepGen's Enhanced Delivery Oligonucleotide, or EDO, platform is founded on over a decade of research and development and leverages cell-penetrating peptides to improve the uptake and activity of conjugated oligonucleotide therapeutics. Using these EDO peptides, we are generating a pipeline of oligonucleotide therapeutic candidates that target the root cause of serious diseases. For more information, visitwww.pepgen.com or follow PepGen onTwitterandLinkedIn.
EEO Statement
PepGen is an Equal Opportunity Employer committed to a culturally diverse workforce. All qualified applicants will receive consideration for employment without regard to race; color; creed; religion; national origin; age; ancestry; nationality; marital, domestic partnership or civil union status; sex, gender, gender identity or expression; affectional or sexual orientation; disability; veteran or military status or liability for military status.
Recruitment & Staffing Agencies
PepGen does not accept unsolicited agency resumes. Currently, we are working exclusively with The Bowdoin Group for all of our recruiting needs. Thank you.