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Associate Scientist II, Imaging & Pharmacology

Perceptive Inc.
Needham, MA Full Time
POSTED ON 2/5/2025
AVAILABLE BEFORE 3/6/2025

Job Purpose

Perceptive is seeking an Associate Scientist II to contribute to in vivo small animal molecular imaging studies, including nuclear medicine techniques (PET/SPECT), computed tomography (CT), and magnetic resonance imaging (MRI) within a multi-modal imaging laboratory. This role supports the development of novel therapeutics by conducting in vivo pharmacology procedures, operating advanced imaging equipment, and effectively communicating data and project updates. The position offers opportunities for rapid technical growth and hands-on experience with cutting-edge pharmaceutical research projects.


Key Responsibilities

· Conduct hands-on animal research using advanced instrumentation with mentorship from leading medical imaging scientists, while collaborating within a matrix environment with research staff, project management, and image analysis teams.

· Follow and execute laboratory specific SOP’s related to role

· Assess study protocols for experimental details (with limited supervision)

  • Participate in protocol reviews
  • Lead projects and schedule necessary task
  • Meet timelines related to protocol execution

· Learn technical/theoretical applications involved in executing pre-clinical studies

· Maintain clear and concise laboratory notes

· Perform data quality control and upload relevant documents upon study completion (with limited supervision)

· Work with IACUC to implement and ensure compliance of animal use protocols

· Assess animal health conditions, communicate with Attending Veterinarian (AV) and provide necessary animal health care (with limited supervision)

· Execution of (with limited supervision):

  • Efficacy studies
  • Biodistribution studies
  • Pharmacokinetic studies
  • Toxicokinetic studies
  • Xenograft models

· Preferred functioning set of classical skills:

  • Test article administration IV, IP, SC, IM, PO
  • Perfusion
  • Compound handling
  • Tissue resection
  • Biological sampling procedures

·Work with radioactive and BSL2 samples and test articles (with limited supervision)

  • Gamma counting
  • Sample disposition
  • Proper handling and disposal of associated materials

Other Duties as assigned


Functional Competencies (Technical knowledge/Skills)

· Understanding of biology, pharmacology, or small animal imaging in the context of pharmaceutical research

· Organized with ability to multi-task

· Comfort with various computer operating systems and programs

· Strong written and oral communication skills

· Occasional weekend and after-hours work as needed

· Ability to lift 50 pounds


Highly Desired Competencies

· Previous experience with medical imaging equipment and with research involving radioactive imaging agents

· Hands on experience as a Nuclear Medicine Technician or Radiology Technician

· Test article administration IV, IP, SC, IM,PO

· Perfusion

· Tissue resection

· Microdissection of tissues (lymph nodes, specific brain sections, etc)

· Biological sampling procedures

· Experience working with BSL2 animals and samples

· Experience with IACUC/Animal Inventory management system


Experience, Education, and Certifications

· AS 3 yrs, BS 1 yrs or MS 0 yrs experience in bioengineering, biomedical engineering, medical physics, radiologic sciences, pharmacology, Biology, Animal Science or a related

field· Experience should include academic or industrial projects utilizing imaging technology, programming, pharmacology or other applicable engineering s

kills· Relevant experience – basic animal handling, pre-clinical or clinical imaging, handling of radioactivity· Experience using tools to communicate progress to Stakeholders.

Salary : $64,000 - $82,000

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