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Cellular Genomics Scientist

pfizer
Cambridge, MA Full Time
POSTED ON 1/22/2025
AVAILABLE BEFORE 3/21/2025

Cellular Genomics Scientist

Summary:

We are seeking a scientist to join our Systems Immunology Lab in Pfizer’s Inflammation & Immunology Research Unit. The successful candidate will be responsible for generating and processing single-cell, spatial, and functional genomics data, as well as supporting standard immunoprofiling activities such as cell culture and flow cytometry.

Responsibilities:

  • Participate in sample collection of murine and human tissues, including the preparation of tubes, interfacing with in vivo scientists to retrieve samples, isolation of primary immune cells, and standard mammalian cell culture
  • Participate in sample preparation of murine and human tissues, including tissue fixation, dissociation, sectioning, and antibody staining
  • Generate spatial and single-cell data via a number of commercial workflows, including 10x Genomics and Parse Technologies
  • Interpret quality control metrics for spatial, single-cell and cytometry experiments

Qualifications:

  • Master's degree with a minimum of 3 years of experience in Biology, Immunology, or a related field OR;
  • PhD with 0 years of experience in Biology, Immunology, or a related field
  • A minimum of 3 years of hands-on experience with standard immunoprofiling technologies including:
  • Flow Cytometry
  • Single-cell library preparation (ideally 10x Genomics or Parse Technology)
  • Preparation and loading of Illumina sequencing libraries
  • Generation of spatial transcriptomics data (any technology) preferred
  • A minimum of 3 years of experience with primary immune cells, including:
  • Primary immune cell isolation
  • Maintenance of immune cell lines
  • Cell culture and in vitro stimulation of primary immune cells
  • Experience with CRISPR-mediated functional genomics, including electroporation of primary immune cells preferred

Location:

  • This is a fully onsite role in Cambridge, MA

Please note contractors are engaged to provide services to Pfizer temporarily in connection with a specific assignment. Contractors are hired and employed through Atrium, our third-party payrolling partner.


This job posting is for a temporary role as an employee of Atrium on assignment at Pfizer. The individual selected for this role will be offered the role as an employee of Atrium; compensation, medical benefits, fringe benefits, and other terms and conditions of employment shall be presented by Atrium upon offer. The pay rate range provided is a reasonable estimate of the anticipated compensation range for this job at the time of posting. The actual pay rate will be based on several factors, including skills, competencies, experience, location and/or being pursued, and other job-related factors permitted by law. In addition, this role will be eligible for overtime pay, in accordance with federal and state requirements.

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