Director ,Pharmacometrics, clinical pharmacology and translational medicine

Please review the listings below of currently available job openings.Director, Pharmacometrics, Clinical Pharmacology and Translational Medicine Location : Nutley, NJType : Direct HireID : j-299Posted : Feb 14, 2025My client is searching for a creative, resourceful, integrative thinker who is driven to use cutting-edge modeling approaches to advance the clinical and translational research in the Neuroscience Business Group. This individual will provide scientific leadership to develop and execute impactful pharmacometric strategies in support of key decisions for programs across all phases of drug development. The complexity and scale of data being generated has grown significantly and requires strong scientific contributions to integrate different approaches in modeling, statistics, and data science to bring value to the Company portfolio. This role requires diverse modeling experience in drug development within pharma / biotech, agility in being able to handle both hands-on modeling and strategic leadership for a dynamic project portfolio, and a strong track record of scientific and collaborative leadership in complex projects and initiatives.Essential Functions In-depth modeling skills, ability to translate complex problems into incisive models.Develop and execute population PK, exposure response, mechanistic PK / PD models of neurodegenerative diseases, including physiologically-based pharmacokinetic (PBPK), quantitative system pharmacology (QSP) models, clinical trial simulations, literature meta-analysis, machine-learning / deep learning, and other state-of-the-art quantitative techniques.Leverage pharmacometrics to make impactful contributions in drug development decision-making and regulatory submissions.Represent Pharmacometrics and effectively communicate pharmacometric input to key management and decision boards.Develop pharmacometrics strategies for Translational Medicine (in particular using continuous, longitudinal biomarkers) and various big, digital, historical data groups and initiatives.Qualifications PhD or PharmD in Pharmaceutical Sciences, Clinical Pharmacology, Applied Mathematics, Engineering, or related area with a strong background in the application of mathematical and statistical methods with 7 years of experience.Proficiency in Non-linear mixed effects (NLME), mechanistic modeling approaches, and using NONMEM, Monolix, R, Matlab, or other modeling software.Proficiency in written and verbal communication, interdisciplinary collaboration, and problem scoping and planning.Experience and disease knowledge in neuroscience is preferable.#J-18808-Ljbffr