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Director, Data Science (Biotech)

PharmaEssentia U.S.A.
Bedford, MA Full Time
POSTED ON 4/24/2025
AVAILABLE BEFORE 7/21/2025
Job Title: Director, Data Science
Location: Bedford MA
Department: Research Data Science / AI & Computational Biology
Reports To: Director, Ops and Data Sciences

Job Summary:
We are seeking a highly skilled Director of Data Science to lead the data-driven innovation effort within our multidisciplinary research teams. This individual will apply advanced analytical methods, AI/ML, and statistical modeling to accelerate the drug discovery and decision-making process in support of PIRC’s expanding research pipelines. The ideal candidate will have deep expertise in computational biology, machine learning, and data-driven drug discovery and will work closely with our Immunology, Translational Science, and Biologics teams in the Boston area as well as Taipei, Taiwan to develop state-of-the-art solutions for drug discovery.

Key Responsibilities:
Data Science & AI/ML Innovation:
  • Develop and apply advanced AI/ML models (e.g., deep neural networks, Bayesian optimization, active learning, LLMs, etc.,) to bring computational methods to the forefront of our drug discovery programs.
  • Integrate and analyze -omics data (including transcriptomic and genomic data) for therapeutic target discovery and indication finding.
  • Provide data-driven recommendations on target ID, validation, translational research and clinical trials to support drug discovery and development efforts.
  • Contribute to and identify opportunities for our computational discovery strategy including long-term investments in technology and talents.
  • Work across therapeutic areas to drive impact in research programs, including Cytokine, Immune-Checkpoints, bispecific ADC.
  • Conduct hands-on analysis of internal and external datasets to generate actionable scientific insights.
Collaboration & Cross-Functional Leadership:
  • Collaborate with cross-functional teams, including R&D, bioinformatics, and clinical scientists, to develop data-driven solutions supporting processes and workflows for data flows, data mapping, data security and data QC.
  • Establish and manage external collaborations with academia, industry partners, and technology platforms to stay at the cutting edge of Computational method development.
  • Mentor junior Data scientists and foster a collaborative, high-performance research environment.

Qualifications:
Required:
  • Ph.D. in Computational Biology, Computer Science, Data Science, Biostatistics, or a related field.
  • 10 years of experience in computational research, with industry experience and people management preferred.
  • Proven expertise in AI/ML development and applications, including deep learning, Bayesian optimization, and active learning.
  • An understanding of drug discovery and biomarker related platforms (NGS, -omics study, Flow Cytometry, etc.), and the types of data generated from such platforms, is highly desirable.
  • Demonstrated experience in managing biomarker or bioassay data in oncology studies is also desirable.
  • Proficiency in R, Python, C/C , shell scripting, and command-line tools.
  • Experience working in Linux, high-performance computing (HPC), and cloud computing environments.
  • Strong publication track record in high-impact peer-reviewed journals and experience advancing molecules from discovery to development is required
  • Excellent interpersonal and communication skills with the ability to collaborate across disciplines.

EEO Statement:
At PharmaEssentia Innovation Research Center (PIRC), we are committed to providing an environment of mutual respect where equal employment opportunities are available to all applicants without regard to race, color, religion, sex, pregnancy (including childbirth and related medical conditions), national origin, age, physical and mental disability, marital status, sexual orientation, gender identity, gender expression, genetic information (including characteristics and testing), military and veteran status, and any other characteristic protected by applicable law. PIRC believes that diversity and inclusion among our team are critical to our success as a global company, and we seek to recruit, develop and retain the most talented people from a diverse candidate pool.  PIRC does not accept unsolicited agency resumes. Staffing agencies should not send resumes to our HR team or to any PIRC employees. PIRC is not responsible for any fees related to unsolicited resumes from staffing agencies.

At PharmaEssentia, our goal is to treat as many people with cancer as possible. That means challenging the status quo with better science that leads to better lives. By joining our team, you will not only expand your own possibilities, but you will contribute to expanding options for people with cancer.

https://us.pharmaessentia.com/careers/

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