Senior Scientist

Job Summary: Provide bioanalytical method development for quantitative analysis of test compounds in biological matrices obtained from a variety of studies for non-GLP and GLP regulated studies.    Essential Functions:    Develop, optimize, and validate LC-MS/MS bioanalytical methods within biological matrices with high technical level report writing upon completion of study Develop and implement assays for bioanalysis of small molecules, peptides, and amino acids in both a non-GLP regulated and GLP regulated environment Perform instrumentation qualifications, calibrations, and verifications Use and maintenance of Sciex (Analyst® Software) and Thermo Scientific (Xcalibur® software) triple quadrupole mass spectrometers Experience in PK study design, data interpretation, and analysis Additional Responsibilities:   Good written and oral communication, and organizational skills are mandatory.   Job Qualifications:  General Knowledge, Skills, and Abilities (KSA’s) required   Experience with method development, executing, and troubleshooting LC-MS/MS assays Experience with sample extraction techniques such as PPT, SLE, and derivatization Time management, organizational skills, and a high level of attention to detail Ability to work effectively as both an individual contributor and in a collaborative team setting. Knowledge regarding troubleshooting techniques of bioanalytical assay method development, qualification, validation, and sample analysis Experience in the application of Good Laboratory Practices (GLP) to provide accurate documentation of analytical results Experience using laboratory equipment including HPLC-MS/MS, Precellys® tissue homogenizer and routine equipment used for sample preparation. Knowledge of or capability to learn Analyst®, Excalibur®, LCQuan® and Microsoft® Office software platforms. Knowledgeable in the application of Good Laboratory Practices (GLP) to provide well-regulated and accurate documentation of analytical results for inclusion into regulatory documents.   Physical Demands: Physical, Mental and workplace Environment Conditions    Attention to detail regarding safety and accuracy of procedures performed. Lite lifting of up to 20lbs. may be required. Working Conditions: Workplace Environment Conditions  Position functions are performed in an office and laboratory environment.   Education and Experience:  Position requires a minimum of a Bachelor’s degree in chemistry, biochemistry, biology, pharmacy or a related discipline, plus a minimum 10 years of applicable lab bench experience.   We Offer: Medical, Dental & Vision Insurance Short and Long Term Disability Life Insurance Paid Vacation, Holidays, and Sick Time 401(k)   Visit us at https://www.pharmoptima.com/   Genesis Pharmoptima is an equal opportunity employer.