Scientist-Immune Oncology

About Pledge Therapeutics

PledgeTX is an exciting new company launched by experienced scientists and successful biotech veteran entrepreneurs. We are developing multiple, first-in- class, small molecule medicines against challenging drug targets across a wide range of disease areas that include viral and immune diseases.

Our efforts have given rise to a constellation of exciting discoveries, spanning early drug hits to preclinical candidates. Our success is based on the rapid translation of clinical and disease insights into target identification and development of novel drug molecules. At the core of our effort is the integration of structural and biophysical knowledge of disease targets to accelerate the pace and success of drug development. We pride ourselves on working with the brightest researchers, partnering with leading drug development teams across the globe to realize our mission of improving the lives of patients.

Job Description: Scientist Immune-Oncology

We seek an enthusiastic, driven and creative scientist capable of solving the challenges associated with drug discovery. The successful candidate will work with an international and multidisciplinary team of scientists engaging different research arms of the company including protein production, assay development and cellular biology for drug screening. Exposure to drug discovery and cell-based oncology/immunology assays will be preferred.

The ideal candidate will have exceptional communication skills, superior technical skills, and exemplary attention to detail. This position will have the opportunity to become part of a dynamic, interdisciplinary R&D team and make significant scientific contributions to numerous drug discovery projects. There will be substantial opportunities to grow with the company.

Responsibilities:

• Conduct research to investigate the effect of small molecules and biologics on function of T and NK cell
• Develop a research strategy with guidance from the team leader, propose strategic vision and program goals
• Establish and execute variety of biochemical/cell-based immunological in vitro assays
• Independently analyze, interpret, and present data at internal meetings
• Maintain experimental records in electronic notebook
• Review literature and propose new experimental strategies/approaches
• Collaborates cross-functionally with other team members to ensure that daily operations and timelines are met.
• Participate in the mentoring and training of junior team members

Education and Experience:

• PhD with 0-5 years of relevant experience in immuno-oncology or immunology in laboratory research settings
• Expertise in T and NK cell killing experiments
• Extensive hands-on experiences with multi-color FACS (12 ), ELISA, western blot and cell-based assays to analyze immune cells in BSL2 laboratory
• Proficiency in GraphPad and Flow Jo
• Ability to work independently with minimal supervision
• Strong analytical, organizational, communication and time management skills
• Able to work in a team and willing to present data to our international partners
• Fluent in English

If you are ready to contribute to innovative research projects and be part of a growing company that is tackling some of the most pressing healthcare issues in modern medicine, please send us your CV and cover letter to mmartin(at)pledge-tx.com

Job Type: Full-time, USA work permit, Equal Opportunity Employment

Job Type: Full-time

Pay: $95,000.00 - $115,000.00 per year

Schedule:

• Monday to Friday

Ability to commute/relocate:

• Canton, MA 02021: Reliably commute or planning to relocate before starting work (Preferred)

Work Location: One location

Salary : $95,000 - $115,000