Demo

Director/Sr. Director, Computational Biology Test Development

Precede
Boston, MA Full Time
POSTED ON 2/13/2025
AVAILABLE BEFORE 4/13/2025

The Opportunity 


We are seeking a senior level computational biology / bioinformatics scientist with background in diagnostic test development and a focus on NGS and ideally epigenomic modalities. This role is responsible for the data analysis and development aspects of clinical diagnostic testdevelopment for a novel blood-based epigenomic platform, as well as analysis relating to the development of the platform itself. This is a unique opportunity for someone passionate about pushing the boundaries of diagnostic testing, building novel diagnostic tests and methods for assay characterization and optimization, and ultimately improving data interpretation to create better predictors and diagnostics. If you're excited about joining an early-stage company with an experienced team operating at a rapid pace, and applying a novel platform for clinical diagnostics testing, this could be your perfect match. 


About Us 


We are pioneering an advanced, minimally invasive, comprehensive epigenomics platform with the potential to profoundly impact the research and development of new medicines and the use of approved medicines in clinical practice across a number of conditions, including cancer. More information on our company and platform can be found on our company website and in our recent publication in Nature Medicine. 


We care deeply about creating a place where folks can do their best work from the start and have intentionally created an environment that is defined by purpose, teamwork, and excellence. This means nurturing team spirit, facing challenges together, collaboratively solving complex problems, while also ensuring a strong focus on individual initiative, accountability, and delivery. 

\n


What You'll Do
  • Develop computational approaches for characterizing the performance of existing and new epigenomic assays and tests. 
  • Define and implement metrics and analyses to assess NGS and epigenomic data quality to enable coordinated optimization of assay and diagnostic performance to address test requirements. 
  • Assume responsibility for the computational aspects of late-stage development and validation of novel epigenomic liquid biopsy diagnostic tests. 
  • Take part indesign and execution of validation studies of epigenomic-based diagnostic tests for use in a regulated clinical lab.  
  • Share data driven insights of test and assay performance with leadership and wet lab development teams to inform assay development priorities. 
  • As a key member of a cross-functional team, you will work closely with various stakeholders, especially those within our platform development laboratory team and regulatory team, to make innovative diagnostics a reality.  


Who You Are
  • PhD or MSc in bioinformatics, computational biology or related field 
  • 5 years experience industry experience, within multidisciplinary R&D group. Management experience is desirable.  
  • You have experience developing a prototype NGS-based diagnostic from a research tool to a clinically validated and approved diagnostic test. Experience in development within a regulated environment (CLIA, FDA) is a plus. 
  • You have an in-depth understanding of the analyses that enable a given regulatory path for a liquid biopsy diagnostic test.  
  • You have spent large parts of your career thinking deeply about high throughput data; how to test its limits and enable better understanding through enhanced characterization of data, with a desired emphasis on NGS data. 
  • You have experience in using computational analyses to understand complex data sets. 
  • You are comfortable presenting your findings in a group setting and advocating for your strategy with leadership. 
  • You are excited by challenging problems and a fast-paced work environment. 
  • You thrive in startup culture, comfortable taking on new projects with minimal direction, and are adaptive in response to feedback and evolving information. 
  • You are proficient in either R (Bioconductor) or Python. 
  • You value diversity, learning from various perspectives, and working collaboratively on multidisciplinary teams. 
  • in response to feedback and evolving information. 
  • You are proficient in either R (Bioconductor) or Python. 
  • You value diversity, learning from various perspectives, and working collaboratively on multidisciplinary teams. 


\n

We believe in building an inclusive and balanced team. We also know meeting every single-exact-criteria can get in the way of meeting stellar folks. Please don’t hesitate to apply! 

We are an equal opportunity employer. We do not discriminate in regard to race, color, religion, national origin, age, sex, sexual orientation, gender identity, marital status, ancestry, physical or mental disability, veteran status, or any other legally protected characteristics. 

If your compensation planning software is too rigid to deploy winning incentive strategies, it’s time to find an adaptable solution. Compensation Planning
Enhance your organization's compensation strategy with salary data sets that HR and team managers can use to pay your staff right. Surveys & Data Sets

What is the career path for a Director/Sr. Director, Computational Biology Test Development?

Sign up to receive alerts about other jobs on the Director/Sr. Director, Computational Biology Test Development career path by checking the boxes next to the positions that interest you.
Income Estimation: 
$219,423 - $248,819
Income Estimation: 
$280,031 - $485,657
Income Estimation: 
$225,010 - $318,974
Income Estimation: 
$270,404 - $352,260
Income Estimation: 
$274,110 - $349,046
Income Estimation: 
$285,744 - $364,577
Income Estimation: 
$182,205 - $244,055
Income Estimation: 
$285,744 - $364,577
Income Estimation: 
$309,148 - $425,307
Income Estimation: 
$319,578 - $425,885
Income Estimation: 
$125,958 - $157,570
Income Estimation: 
$120,989 - $162,093
Income Estimation: 
$74,806 - $91,633
Income Estimation: 
$71,928 - $87,026
Income Estimation: 
$145,337 - $174,569
Income Estimation: 
$145,337 - $174,569
Income Estimation: 
$153,127 - $203,425
Income Estimation: 
$139,626 - $193,276
Income Estimation: 
$164,650 - $211,440
Income Estimation: 
$130,030 - $173,363
View Core, Job Family, and Industry Job Skills and Competency Data for more than 15,000 Job Titles Skills Library

Not the job you're looking for? Here are some other Director/Sr. Director, Computational Biology Test Development jobs in the Boston, MA area that may be a better fit.

Director of Computational Biology

Society for Conservation Biology, Boston, MA

Senior Medical Director, Clinical Development Hematology

10001120 - Director Clinical Dev, Boston, MA

AI Assistant is available now!

Feel free to start your new journey!