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Clinical Laboratory Scientist

Prelude Corporation
Laguna Hills, CA Full Time
POSTED ON 2/5/2025
AVAILABLE BEFORE 5/2/2025

Job Description

Job Description

Description :

Full-Time Monday-Friday 8am-5pm

We are seeking a highly motivated and skilled licensed CLS to join our team. The ideal candidate will have experience in running Next Generation Sequencing (NGS) and knowledge of molecular biology techniques.

Responsibilities

  • Ensure that the equipment is calibrated, maintained, and operated according to the manufacturer's guidelines and standard operating procedures.
  • Adheres to the CAP, CLIA and NYS regulations.
  • Run protocols for sample collection, processing, storage, and tracking in LIMs to ensure the integrity and traceability of the samples throughout the NGS workflow.
  • Run clinical and R&D samples for NGS and molecular biology techniques, including microdissection, FFPE nucleic acid extraction, NGS library preparation, sequencing, data analysis, and quality control measures with appropriate NGS controls.
  • Perform and train other CLS’s on established NGS and molecular biology procedures, including macrodissection, FFPE nucleic acid extraction, NGS library preparation, sequencing, and data analysis, including quality control measures.
  • Perform validation testing to ensure with selected reagents and controls to ensure the assay meets the required performance specifications.
  • Perform validation studies to assess the performance characteristics of the NGS assay, including sensitivity, specificity, accuracy, precision, and reproducibility.
  • Analyze and interpret data using appropriate statistical methods and software, including sensitivity, specificity, accuracy, precision and reproducibility.
  • Maintain accurate records and documentation of experiments and results.
  • Reporting to the General Laboratory Supervisor.

Requirements :

  • Minimum 4 years as a certified or licensed clinical laboratory scientist
  • California Clinical Laboratory Scientist (Highly Preferred : California Clinical Genetic Molecular Biologist Scientist license - CGMBS.)
  • Must be well-organized, open-minded, decisive, and flexible. They must be able to communicate well with others, and work as a team. Good writing skills and and extensive computer experience are necessary
  • Experience with Macrodissection, RNA extraction and downstream analysis
  • Strong experience in development of targeted library, conducting sequencing NGS library preparation, sequencing, and data analysis
  • Experience in project management and organization
  • Excellent record-keeping and documentation skills
  • Strong communication skills and ability to work in a team-oriented environment
  • Validation and SOP writing experience a plus
  • Must have superior work ethic, high energy level and be results oriented
  • Internally motivated and self-starter; ability to make an impact
  • Comfortable in a fast-paced environment
  • Excellent oral and written communication skills
  • Candidate must be a fast learner, naturally oriented toward problem solving, have superior work ethic, high energy level and be ambitious; good organizational skills
  • Education

  • Preferred Bachelor's or Master's degree in Molecular Biology, Biochemistry, or related field
  • CLS license 4 years
  • Highly Preferred : California Clinical Genetic Molecular Biologist Scientist license - CGMBS
  • Anatomic or Clinical Pathology experience
  • Prior experience with NextGen sequencing instruments.
  • Minimum of 4 years of molecular and histology experience within an anatomic pathology laboratory or clinical laboratory.
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