What are the responsibilities and job description for the CGT Process Development Intern position at ProBio?
About GenScript
GenScript Biotech Corporation (Stock Code: 1548.HK) is a global biotechnology group. Founded in 2002, GenScript has an established global presence across North America, Europe, the Greater China, and Asia Pacific. GenScript's businesses encompass four major categories based on its leading gene synthesis technology, including operation as a Life Science CRO, enzyme and synthetic biology products, biologics development and manufacturing, and cell therapy.
GenScript is committed to striving towards its vision of being the most reliable biotech company in the world to make humans and nature healthier through biotechnology.
About ProBio
ProBio proactively provides end-to-end CDMO service from drug discovery to commercialization with proactive strategies, professional solutions and efficient processes in cell and gene therapy (CGT), vaccine, biologics discovery and antibody protein drug to accelerate drug development for customers. ProBio’s total cell and gene therapy solution covers CMC of plasmid and virus for IND filing as well as clinical manufacturing and commercial manufacturing. In terms of plasmid service, ProBio supports the most clinical approvals for CGT drugs including mRNA vaccines, CAR-T in China. It is also the first GMP manufacturing platform to provide in vitro transcription (IVT) template linearized plasmids for mRNA vaccines and has supported several mRNA vaccine global enterprises to obtain clinical approvals. In terms of viral vector service, ProBio has a stable and high-yield viral vector platform.
Job Scope
The position reports to the Sr. Scientist, Viral Vector Process Development & MSAT Department. This role is ideally suited for a dynamic bench-focused individual to support translation of research process to GMP-compliant manufacturing. This is a great opportunity to join a fast-paced company, develop, and expand technical expertise while gaining core competency in the biotechnology/life sciences industry.
The individual must currently be an active student in either and undergraduate or graduate program
Responsibilities
#LW
GenScript USA Inc/ProBio Inc. is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is the Company's policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by law.
GenScript USA Inc./ProBio Inc. maintains a drug-free workplace.
GenScript Biotech Corporation (Stock Code: 1548.HK) is a global biotechnology group. Founded in 2002, GenScript has an established global presence across North America, Europe, the Greater China, and Asia Pacific. GenScript's businesses encompass four major categories based on its leading gene synthesis technology, including operation as a Life Science CRO, enzyme and synthetic biology products, biologics development and manufacturing, and cell therapy.
GenScript is committed to striving towards its vision of being the most reliable biotech company in the world to make humans and nature healthier through biotechnology.
About ProBio
ProBio proactively provides end-to-end CDMO service from drug discovery to commercialization with proactive strategies, professional solutions and efficient processes in cell and gene therapy (CGT), vaccine, biologics discovery and antibody protein drug to accelerate drug development for customers. ProBio’s total cell and gene therapy solution covers CMC of plasmid and virus for IND filing as well as clinical manufacturing and commercial manufacturing. In terms of plasmid service, ProBio supports the most clinical approvals for CGT drugs including mRNA vaccines, CAR-T in China. It is also the first GMP manufacturing platform to provide in vitro transcription (IVT) template linearized plasmids for mRNA vaccines and has supported several mRNA vaccine global enterprises to obtain clinical approvals. In terms of viral vector service, ProBio has a stable and high-yield viral vector platform.
Job Scope
The position reports to the Sr. Scientist, Viral Vector Process Development & MSAT Department. This role is ideally suited for a dynamic bench-focused individual to support translation of research process to GMP-compliant manufacturing. This is a great opportunity to join a fast-paced company, develop, and expand technical expertise while gaining core competency in the biotechnology/life sciences industry.
The individual must currently be an active student in either and undergraduate or graduate program
Responsibilities
- Hands-on experimental work in the development and optimization of upstream unit operations (cell culture, transfection, and harvest/clarification) for viral vector manufacturing process.
- Contribute to the planning and execution of cell-culture related experiments to analyze, interpret, and report data summary packages.
- Collaborate with internal/external partnerships to evaluate and implement new bioprocessing technologies and strategies.
- Collaborate with cross functional leads (Manufacturing, Quality Assurance, Quality Control) to support process technology transfer, cGMP risk evaluation, and deviation management.
- Maintain and follow detailed and comprehensive batch records.
- Support scientists in PD viral vector production/purification process
- Learn and perform core bioprocessing techniques such as cell culture, Single Use bioreactor production, Ultrafiltration/Diafiltration and chromatography purification.
- Review and assess production materials purchasing, storing, and monitoring
- Participate in team group discussions as well as the intradepartmental meetings
- Presentation of final project summary in functional subgroup
- Read and understand scientific literature in gene and cell therapy, use the knowledge to generate ideas and contribute to process design and development.
- Must currently be an active student pursuing a Bachelor’s or Master’s degree with 0-1 years of experience in Biology, Biochemistry, Immunology, Chemical Engineering or equivalent in biotech development with particular experience in gene and cell therapy product design. Experience with Oncolytic, Lentivirus, AAV process development for oncology a plus.
- Previous wet lab experience cell culturing, chromatography, and/or PCR is preferred.
- Good understanding of Design of Experiment and statistical analysis.
- Strong interpersonal, time management, and oral/written communication skills.
#LW
GenScript USA Inc/ProBio Inc. is a proud equal opportunity/affirmative action employer committed to attracting, retaining, and maximizing the performance of a diverse and inclusive workforce. It is the Company's policy to ensure equal employment opportunity without discrimination or harassment based on race, color, religion, sex (including pregnancy, childbirth, or related medical conditions), sexual orientation, gender identity or expression, age, disability, national origin, marital or domestic/civil partnership status, genetic information, citizenship status, uniformed service member or veteran status, or any other characteristic protected by law.
GenScript USA Inc./ProBio Inc. maintains a drug-free workplace.
