Senior Software Engineer - Backend

This position will be on-site at Proscia's Headquarters in Philadelphia, PA. 

About Proscia

Pathology is at the center of medicine and is undergoing a profound transformation as the final frontier of digitization in healthcare. We started Proscia to accelerate pathology’s transition from microscope to images—and to use AI to change the way we think about cancer.

We can’t change medicine alone. That’s why we’re looking for curious thinkers, big dreamers, developers, evangelists, pathologists, and scientists— exceptional talent to help us harness the great power of AI for good and advance humankind.

At Proscia, we push the limits of medicine and technology, solving problems the world has never solved before. We build software used by thousands of scientists and pathologists working on the front lines of fighting big enemies like cancer for patients around the globe. To accelerate our vision, Proscia has raised over $100M in capital from world-class healthcare and technology investors.

About the Role
As a Senior Software Engineer, you’ll play a key role in designing and implementing the full application stack of our digital pathology platform. The ideal candidate will have extensive experience with Node.js for backend development, strong database skills in enterprise environments, as well as some experiences in developing reactive Web applications, particularly single-page applications using the Vue framework. This role involves designing, developing, testing, and deploying robust and scalable applications.

You will work closely with our cross-functional engineering and operation teams to create an enterprise level application that is easily deployable in AWS and highly serviceable. Candidates should have strong proficiency in Node.js, Postgres, TypeScript, high-performance enterprise applications and a deep passion for delivering high-quality software solutions.

Key Responsibilities:

• Design and implement backend services
• Participate in a high-performing Agile/Scrum team to define, plan, and deliver high-impact features
• Coordinate and integrate with other engineering teams across Proscia to align with shared goals and ensure seamless interoperability
• Champion AI-first problem-solving approaches by incorporating AI/ML tools to improve development processes and platform capabilities
• Contribute to architectural decisions and best practices, ensuring the scalability and maintainability of the product
• Create integrations with third-party applications to enhance the capabilities of Concentriq products
• Ensure solutions meet regulatory, quality, and performance standards required for healthcare applications
• Continuously explore new technologies, libraries, and frameworks to enhance the platform

Required Experience:

• Candidates should have a minimum of 5 years of professional software engineering experience
• Extensive experience developing REST APIs with Node.js using Typescript
• Use of Postgres in an enterprise application environment including both ORM and direct SQL integration
• Load balancing and performance optimizations
• Strong test automation skills including experience with Vitest or other automated testing frameworks
• Familiarity with version control systems like Git, and experience working in Agile/Scrum development environments
• Excellent problem-solving skills, attention to detail, and a commitment to delivering high-quality user experiences
• Experience with cloud platforms (e.g., AWS, Azure, Google Cloud).
• Familiarity with containerization technologies (e.g., Docker, Kubernetes).
• Knowledge of CI/CD pipelines
• Experience with Agile development methodologies
• Excellent communication and teamwork abilities

Desirable Experience:

• Experience designing and scaling distributed systems in production environments
• Familiarity with microservices architecture and trade-offs between monolith and service-oriented designs
• Experience with Vue or a similar frontend framework (Angular/React), including state management, component design, and performance optimization
• Understanding of event-driven patterns and practical experience with message queues (e.g., RabbitMQ, Kafka, or AWS SQS)
• Knowledge of database performance optimization strategies, such as partitioning, indexing, and connection pooling
• Experience with infrastructure as code (e.g., Terraform, CloudFormation) and deploying highly available systems in AWS
• Exposure to load balancing strategies, caching layers (e.g., Redis), and API gateway usage in cloud environments
• Experience participating in architectural reviews and translating system design discussions into implementation plans

Beyond Just Work

Being a Proscian means believing in a mission, overcoming challenges in the journey together, and sharing in what success brings. We believe that every major growth period creates an exceptional career runway. We’re here to change the world together and empower each other to become our best selves in the process.

As a company in the healthcare field, we want our people to be happy and healthy, in and out of the office. In addition to competitive pay, we ensure everyone on our team is supported with savings, schedule, and insurance options that promote long-term health and personal growth.

At Proscia, we don’t just accept difference — we celebrate it, we support it, and we thrive on it for the benefit of our employees, our products, and our community. Proscia is proud to be an equal opportunity workplace.