What are the responsibilities and job description for the Scientist I, Chemistry position at PTC Therapeutics, Inc?
PTC Therapeutics is a successful global pharmaceutical company. The Scientist I, Chemistry contributes to PTC's drug discovery efforts by synthesizing small molecules in support of internal lead optimization programs. The incumbent is responsible for independently planning and executing synthetic organic chemistry protocols to efficiently obtain desired targets for biological assays and testing. The selected candidate is also responsible for interpreting and communicating experimental results to his/her supervisor and the project team. This role is highly collaborative and involves forming productive relationships in an interdisciplinary team. With the help and coaching of the supervisor, the Scientist I will have the opportunity to develop into a Medicinal Chemist and become well-versed in all aspects of modern drug discovery.Job Description:
ESSENTIAL FUNCTIONS/Key Responsibilities
Primary duties/responsibilities:
With guidance from the advisor, plan, initiate and efficiently execute the synthesis, purification, and characterization of small molecules.
Sustain a high level of productivity in the lab delivering on team goals.
Analyze data, interpret, and communicate results as part of an internal multi-disciplinary team.
Maintain broad knowledge of state-of-the-art principles and theories related to synthetic organic chemistry.
Understand goals & strategies of the project, proactively develop innovative & practical chemistry.
Develop and apply organic chemistry knowledge and skills.
Present findings internally to the Chemistry Department and cross-functional teams.
Participate in the development and writing of patent applications.
Abide by all safety and regulatory guidelines.
Maintain a detailed laboratory notebook.
Assume instrument stewardships (e.g. LCMS, NMR, Lyophilizer etc.)
Perform other tasks as assigned.
Abide by all safety and regulatory guidelines.
Keep laboratory environment safe and well-organized.
KNOWLEDGE/SKILLS/ABILITIES REQUIRED
Transition metal catalysis.
Broad range of organic chemistry knowledge.
Planning and performing complex multi-step organic syntheses, retro-synthetic analysis.
Extensive repertoire of classic and modern reactions including transition metal catalysis.
Strong communication skills, work ethic, enthusiasm, and self-starter mentality.
Creative problem solver in the face of synthesis and project difficulties.
Ability to work collaboratively in a fast-paced, team environment with rapidly changing priorities.
Excellent planning, organization, and time management skills.
Highly goal-driven and detail-oriented. Commitment to continuous learning.
Record of achievement with peer-reviewed publications.
* Minimum level of education and years of relevant work experience.
Ph.D. degree in Organic Chemistry with 0-2 years post-doctoral or industry experience.
* Travel requirements
Up to 10%
*Physical requirements
Laboratory based position
Expected Base Salary Range
$119,600 - $140,700. The base salary offered will be contingent on assessment of candidate education level, background, and experience relative to the requirements of the position they are being considered for, as well as review of internal equity.
In addition to base salary, PTC employees are also eligible for short- and long-term incentives.All eligible employees may also enroll in PTC's medical, dental, vision, and retirement savings plans.
EEO Statement:
PTC Therapeutics is an equal opportunity employer. We welcome applications from all individuals, regardless of race, color, national origin, gender, age, physical characteristics, social origin, disability, religion, family status, pregnancy, sexual orientation, gender identity, gender expression, disability, veteran status or any unlawful criterion under applicable law. We are committed to treating all applicants fairly and avoiding discrimination.
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Salary : $119,600 - $140,700
