What are the responsibilities and job description for the In Vitro Toxicologist position at recursionpharmaceuticals?
Your work will change lives. Including your own.
The Impact You’ll Make
Recursion is at the forefront of reimagining drug discovery through the integration of automated cell biology, high-dimensional and diverse data sets, and sophisticated analytics and machine learning. We are seeking an in vitro toxicologist who can drive a collaborative effort aimed at identifying and validating novel in vitro safety assessments across our diverse portfolio of drug projects. Currently, our high-throughput platform teams utilize technologies such as brightfield cell imaging and phenomics, high-throughput transcriptomics and fast-proteomics coupled with our advanced machine learning analytics to mine the data for novel relationships and to help decode biology. We see broad opportunities to expand the platform for decoding toxicity/safety and we are seeking for someone with the passion to drive this effort. The goal is to build novel, advanced in vitro toxicology screening to the Recursion platform that to predict toxicities such as cytotoxicity, hepatotoxicity, or cardiotoxicity.
Career development opportunities will include the opportunity to work with the early project teams to provide scientific expertise and leadership for the safety assessment of Recursion programs from early discovery through to candidate selection and beyond. You will contribute to the assessment and selection of novel drug targets and the optimisation of novel candidate molecules using innovative molecular and cellular technologies to enhance the safety profile of our drug candidates.
In this role, you will
- Implement innovative experimental or computational strategies using multi-dimensional data to assess and/or provide mechanistic understanding of safety issues.
- Adapt and apply toxicology screening strategies to predict, assess and mitigate on-target, off-target and other drug-related safety risks in support of the drug discovery portfolio.
- Provide subject matter expertise on cross-functional project teams within the discovery organization with an opportunity to oversee the preclinical safety strategy in development as projects progress.
- Act as a key resource for early safety assessment during the discovery phase, providing scientific knowledge and expertise to cross-functional project teams on the appropriate interpretation of in vitro data.
- Collaborate with external collaborators to ensure best practice for in vitro safety assessment.
- Partner with the project teams to develop optimal strategies to address specific safety issues within project teams. Provide verbal and written summaries for internal discussions. Present summary data to project teams, senior leadership and external partners as needed.
The Team You’ll Join
Reporting to the Vice President of Toxicology you’ll be joining a dynamic toxicology team that works across the portfolio to guide projects through the various stages of discovery and development. This high performing team will work together to continually improve our workflows to drive towards greater efficiency and automation.
The Experience You’ll Need
- Pharm D or Ph.D in toxicology, Pathology, Physiology, Biochemistry or expertise in related biological scientific disciplines with preferably 1 or 2 years of postdoctoral experience.
- Background in cell biology and imaging techniques, or molecular biology running transcriptomic or proteomic experiments with experience in designing and developing high throughput screening assays.
- Proven ability to troubleshoot technical issues with biological experiments.
- Skilled in interpreting observed phenotypic signatures to potential mechanisms of toxicity.
- Highly motivated scientist with the ability to work independently as well as collaborate with stakeholders to drive the development of novel toxicology assays.
- Stay informed on the latest trends and advancements in advanced in vitro platforms and physiological models, and their potential applications in improving the predictive power of toxicology studies.
- Keen interest in artificial intelligence and its application to drug discovery. Experience with the use of AI-tools to predict toxicology endpoints.
Working Location & Compensation:
This position is based at our office located in Salt Lake City. Please note that we are a hybrid environment and ask that employees spend 50% of their time in the office. Relocation support can be provided for this role.
At Recursion, we believe that every employee should be compensated fairly. Based on the skill and level of experience required for this role, the estimated current annual base range for this role is $103,000-$175,000. You will also be eligible for an annual bonus and equity compensation, as well as a comprehensive benefits package.
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The Values We Hope You Share:
- We act boldly with integrity. We are unconstrained in our thinking, take calculated risks, and push boundaries, but never at the expense of ethics, science, or trust.
- We care deeply and engage directly. Caring means holding a deep sense of responsibility and respect - showing up, speaking honestly, and taking action.
- We learn actively and adapt rapidly. Progress comes from doing. We experiment, test, and refine, embracing iteration over perfection.
- We move with urgency because patients are waiting. Speed isn’t about rushing but about moving the needle every day.
- We take ownership and accountability. Through ownership and accountability, we enable trust and autonomy—leaders take accountability for decisive action, and teams own outcomes together.
- We are One Recursion. True cross-functional collaboration is about trust, clarity, humility, and impact. Through sharing, we can be greater than the sum of our individual capabilities.
Our values underpin the employee experience at Recursion. They are the character and personality of the company demonstrated through how we communicate, support one another, spend our time, make decisions, and celebrate collectively.
More About Recursion
Recursion is a clinical stage TechBio company leading the space by decoding biology to industrialize drug discovery. Enabling its mission is the Recursion OS, a platform built across diverse technologies that continuously expands one of the world’s largest proprietary biological and chemical datasets. Recursion leverages sophisticated machine-learning algorithms to distill from its dataset a collection of trillions of searchable relationships across biology and chemistry unconstrained by human bias. By commanding massive experimental scale — up to millions of wet lab experiments weekly — and massive computational scale — owning and operating one of the most powerful supercomputers in the world, Recursion is uniting technology, biology and chemistry to advance the future of medicine.
Recursion is headquartered in Salt Lake City, where it is a founding member of BioHive, the Utah life sciences industry collective. Recursion also has offices in London, Toronto, Montreal and the San Francisco Bay Area. Learn more at www.Recursion.com, or connect on X (formerly Twitter) and LinkedIn.
Recursion is an Equal Opportunity Employer that values diversity and inclusion. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, age, disability, veteran status, or any other characteristic protected under applicable federal, state, local, or provincial human rights legislation.
Recursion welcomes and encourages applications from people with disabilities. Accommodations are available on request for candidates taking part in all aspects of the selection process.
Recruitment & Staffing Agencies: Recursion Pharmaceuticals and its affiliate companies do not accept resumes from any source other than candidates. The submission of resumes by recruitment or staffing agencies to Recursion or its employees is strictly prohibited unless contacted directly by Recursion’s internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Recursion, and Recursion will not owe any referral or other fees. Our team will communicate directly with candidates who are not represented by an agent or intermediary unless otherwise agreed to prior to interviewing for the job.
Salary : $103,000 - $175,000