Demo

Principal Scientist, AAV Production Team Lead

Regeneron Pharmaceuticals
TARRYTOWN, NY Full Time
POSTED ON 1/25/2025
AVAILABLE BEFORE 2/21/2025
Job Title: Principal Scientist

Description:
We are currently seeking a motivated Principal Scientist to lead our AAV production team within Regeneron Genetic Medicines (RGM). You will oversee a talented team dedicated to supporting early-stage research for Regeneron's gene therapy portfolio and technology development through production and purification of research-grade AAV.

Daily Responsibilities:
• Directly supervise and manage Regeneron's AAV Research Vector core, setting priorities and goals, facilitating cross-functional collaboration, forecasting demand, developing talent, and interfacing between RGM leadership, requestors, and team members.
• Identify new strategies, instruments, and technologies to improve process yield, turnaround time, efficiency, consistency, and quality.
• Collaborating with other Regeneron cores, technology centers, and therapeutic areas.
• Contributing to departmental, cross-functional, senior leadership, and external meetings by providing expertise and communicating timelines, expectations, and vision.
• Working closely with RGM teams to enable the next generation of gene therapies.
• Providing technical support and assisting teams within the lab.
• Overseeing lab activities and implementation of new technologies and processes.
• Coordinating production teams to maximize effectiveness and streamline workflows.

Requirements:
This might be the right role for you if you:
• Are passionate about genetic medicines and supporting gene therapy development.
• Find yourself at home being close to the bench, but want additional leadership responsibilities.
• Enjoy problem solving and adapting to new technologies and challenges.
• Want to provide meaningful contributions to the development of an organizational culture that supports growth and development of its people and capabilities to drive forward the RGM pipeline.
• Are excited to mentor and develop team members, providing growth opportunities, fostering a collaborative environment, and engaging the team with the impact of their work.

Qualifications:
To be considered for this role, you must have at least a Ph.D. and 5 years or a BS/MS and 15 years of relevant experience in either Chemical Engineering, Biochemical Engineering, Molecular Biology, Gene Therapy or related field. We need someone with a strong foundational understanding of AAV-based gene therapies, protein and/or virus purification, chromatography, process development, and analytical techniques. Must have experience with managing a team and directing the growth and development of our processes and talent. Experience working within or managing a core function or support group is preferred.

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