What are the responsibilities and job description for the Scientist- Protein Purification position at Regeneron?
We are seeking a highly motivated Scientist to join our Protein Development group within the Therapeutic Proteins department. You will support purification & biochemical characterization of protein reagents.
As a Scientist, a typical day might include:
Conducting protein purification using an ÄKTA AVANT or Pure chromatography system
Carrying out LAL (limulus amebocyte lysate) testing for bacterial lipopolysaccharide endotoxin
Doing protein characterization of reagents by Western blotting, SDS PAGE electrophoresis, SEC chromatography, spectrophotometry, etc.
Conjugating protein reagents to biotin, fluorophores (e.g. Alexa & PE), & other tags
Performing antibody purification working in a team for small scale production in a fast pace setting
Conducting protein expression in E. coli, refolding of inclusion bodies, and developing methods of protein purification
Interpreting data & documenting findings in electronic notebook (ELN)
This role might be for you if you:
Can work productively in a fast-paced collaborative team
Have strong organizational skills and excellent verbal and written communication skills
Enjoy working productively in a fast-paced collaborative environment
Have an eye for detail and pride yourself on the quality of your work
Enjoy working on current problems while thinking of future solutions.
In order to be considered for this role , you must have at least a BS/MS in Molecular Biology, Cellular Biology, Biochemistry or related field with 6 years of relevant experience in protein purification/characterization. E.coli expression and purification are required. We need someone with a solid understanding of protein biochemistry. Must have hands on experience with Affinity, Ion Exchange, Reverse Phase, & Size Exclusion chromatography. Experience with automated liquid handlers is advantageous. Experience with Spectrophotometry, SDS-PAGE electrophoresis & Western blotting is required. Additionally, experience with the solubilization, handling, & characterization of peptides is a plus.
Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits, which often include (depending on location) health and wellness programs, fitness centers, equity awards, annual bonuses, and paid time off for eligible employees at all levels!
Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.
For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.
Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.
Salary Range (annually) $92,500.00 - $151,100.00
As a Scientist, a typical day might include:
Conducting protein purification using an ÄKTA AVANT or Pure chromatography system
Carrying out LAL (limulus amebocyte lysate) testing for bacterial lipopolysaccharide endotoxin
Doing protein characterization of reagents by Western blotting, SDS PAGE electrophoresis, SEC chromatography, spectrophotometry, etc.
Conjugating protein reagents to biotin, fluorophores (e.g. Alexa & PE), & other tags
Performing antibody purification working in a team for small scale production in a fast pace setting
Conducting protein expression in E. coli, refolding of inclusion bodies, and developing methods of protein purification
Interpreting data & documenting findings in electronic notebook (ELN)
This role might be for you if you:
Can work productively in a fast-paced collaborative team
Have strong organizational skills and excellent verbal and written communication skills
Enjoy working productively in a fast-paced collaborative environment
Have an eye for detail and pride yourself on the quality of your work
Enjoy working on current problems while thinking of future solutions.
In order to be considered for this role , you must have at least a BS/MS in Molecular Biology, Cellular Biology, Biochemistry or related field with 6 years of relevant experience in protein purification/characterization. E.coli expression and purification are required. We need someone with a solid understanding of protein biochemistry. Must have hands on experience with Affinity, Ion Exchange, Reverse Phase, & Size Exclusion chromatography. Experience with automated liquid handlers is advantageous. Experience with Spectrophotometry, SDS-PAGE electrophoresis & Western blotting is required. Additionally, experience with the solubilization, handling, & characterization of peptides is a plus.
Does this sound like you? Apply now to take your first step towards living the Regeneron Way! We have an inclusive and diverse culture that provides comprehensive benefits, which often include (depending on location) health and wellness programs, fitness centers, equity awards, annual bonuses, and paid time off for eligible employees at all levels!
Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, nationality, national or ethnic origin, civil status, age, citizenship status, membership of the Traveler community, sexual orientation, disability, genetic information, familial status, marital or registered civil partnership status, pregnancy or parental status, gender identity, gender reassignment, military or veteran status, or any other protected characteristic in accordance with applicable laws and regulations. The Company will also provide reasonable accommodation to the known disabilities or chronic illnesses of an otherwise qualified applicant for employment, unless the accommodation would impose undue hardship on the operation of the Company's business.
For roles in which the hired candidate will be working in the U.S., the salary ranges provided are shown in accordance with U.S. law and apply to U.S.-based positions. For roles which will be based in Japan and/or Canada, the salary ranges are shown in accordance with the applicable local law and currency. If you are outside the U.S, Japan or Canada, please speak with your recruiter about salaries and benefits in your location.
Please note that certain background checks will form part of the recruitment process. Background checks will be conducted in accordance with the law of the country where the position is based, including the type of background checks conducted. The purpose of carrying out such checks is for Regeneron to verify certain information regarding a candidate prior to the commencement of employment such as identity, right to work, educational qualifications etc.
Salary Range (annually) $92,500.00 - $151,100.00
Salary : $92,500 - $151,100
