What are the responsibilities and job description for the Computational Clinical Scientist II position at REVOLUTION Medicines?
Revolution Medicines is a clinical-stage precision oncology company focused on developing novel targeted therapies to inhibit frontier targets in RAS-addicted cancers. The company's R&D pipeline comprises RAS(ON) Inhibitors designed to suppress diverse oncogenic variants of RAS proteins, and RAS Companion Inhibitors for use in combination treatment strategies. As a new member of the Revolution Medicines team, you will join other outstanding professionals in a tireless commitment to patients with cancers harboring mutations in the RAS signaling pathway.
The Opportunity :
In this role, you will work within our Translational Medicine group analyzing and interpreting molecular and clinical data. Analysis will focus on using genomic, protein and other targeted assays to identify and validate predictive biomarkers. The computational clinical scientist will work on various projects in different phases of drug development and contribute to the cross-functional team which includes other bioinformaticians, program leads, medical monitors, biostatisticians other pre-clinical scientists.
- Integrate multiple data sources including circulating tumor DNA, patient enrollment data, molecular profiling (RNA / DNA sequencing outputs), multiplex immunohistochemistry to identify and validate new biomarkers for candidate drugs
- Work with internal groups, contract research organizations and collaborators to deliver validated biomarker data and analysis
- Support the development of biomarker related aspects of the trial design where bioinformatic analysis is required, including study protocols, lab manuals, clinical study reports, and other regulatory documents
- Work with biomarker scientists to support analysis of biomarker readouts (summary statistics, and visualization of efficacy in molecular subgroups)
- Collaborate with preclinical bioinformaticians to design, analyze and interpret experiments to validate biomarkers, understand compound mechanism of action, and identify biomarkers for patient selection and target engagement
Required Experience, Skills, and Education :
Preferred Skills :
The base salary range for this full-time position is $172,000 to $198,000 for candidates working onsite at our headquarters in Redwood City, CA. The range displayed on each job posting is intended to be the salary for an individual working onsite in Redwood City and will be adjusted for the local market a candidate is based in. Our salary ranges are determined by role, level, and location. Individual pay is determined by multiple factors, including job-related skills, experience, market dynamics, and relevant education or training.
Please note that base salary is one part of the overall total rewards program at RevMed, which includes competitive cash compensation, robust equity awards, strong benefits, and significant learning and development opportunities.
Revolution Medicines is an equal opportunity employer and prohibits unlawful discrimination based on race, color, religion, gender, sexual orientation, gender identity / expression, national origin / ancestry, age, disability, marital status, medical condition, and veteran status.
Revolution Medicines takes protection and security of personal data very seriously and respects your right to privacy while using our website and when contacting us by email or phone. We will only collect, process and use any personal data that you provide to us in accordance with our CCPA Notice and Privacy Policy. For additional information, please contact privacy@revmed.com.
LI-Hybrid #LI-JC1
Salary : $172,000 - $198,000
