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Senior Manager, Commercial Diagnostics & Bioinformatics

Sarepta Therapeutics, Inc.
Cambridge, MA Full Time
POSTED ON 1/13/2025
AVAILABLE BEFORE 3/13/2025

Why Sarepta? Why Now?
The promise of genetic medicine has arrived, and Sarepta is at the forefront. We hold leadership positions in Duchenne muscular dystrophy (DMD) and limb-girdle muscular dystrophies (LGMDs), and we currently have more than 40 programs in various stages of development in gene therapy, RNA and gene editing. In 2023, we launched our fourth therapy and the first ever gene therapy to treat Duchenne.
 

We’re looking for people who see unlimited potential in themselves and who are motivated by an unwavering commitment to patients.
 

What Sarepta Offers

At Sarepta, we care deeply about all the people in our community and believe in the importance of supporting them in all aspects of their lives. We aspire to maintain a culture that acknowledges people bring their whole selves to work, and we will strive to help everyone in our community integrate their work and personal lives while maintaining productivity. We are committed to offering a range of benefits and work-life resources designed to support people in the following areas:

  • Physical and Emotional Wellness

  • ​Financial Wellness

  • Support for Caregivers
     

For a full list of our comprehensive benefits, see our website: https://www.sarepta.com/join-us
 

The Importance of the Role

The Senior Manager, Commercial Diagnostics & Bioinformatics reports into the Executive Director, Commercial Diagnostics and plays a key role in driving the strategic vision and objectives to make Sarepta a recognized leader in precision genetic medicine for rare diseases. The Senior Manager, Commercial Diagnostics analyzes genetic diagnostic data to provide insights and guidance for the development of potential commercial activities and decision making. This role requires the integration of technical expertise in genetic data analytics and data integration with the ability to understand commercial insights. Success in this highly engaging hands-on role is dependent upon technical/coding expertise, interpretation of data, commercial knowledge, effective collaboration with cross functional departments and proficiency working in a global matrix environment. This role engages with external diagnostic stakeholders and select providers around diagnostic/genetic testing and serves as an internal resource for data strategy and analytics.

The Opportunity to Make a Difference

  • Contribute to the development, execution, and management of a Commercial Diagnostic Data strategy including the following:
    • Oversee and contribute to the genetic and/or other diagnostic data ingestion and reporting processes
    • Conceive, design, perform and deliver ad-hoc and pre-specified genetic data analyses, develop insights and recommendations for internal stakeholders 
    • Identify new data sources/vendors, determine contract requirements, manage contract negotiations, direct day to day activities, and contribute to building new data models
  • Design genetic diagnostic data ingestion and processing pipeline audit logs; monitor the audit process to maintain data integrity and ensure quality data sets; remediate genetic diagnostic data quality issues with multiple external vendors in a timely manner
  • Develop and implement governance guidelines in conjunction with cross functional partners; provide oversight to ensure that genetic diagnostic data are used appropriately within the organization
  • Collaborate with cross functional partners to leverage available genetic databases for ad-hoc analyses to answer commercially focused questions
  • Drive innovation by embracing ‘connect the dots’ mindset, initiative-taking identification, and dissemination of actionable biological information 
  • Effectively communicate and present analysis results to collaborators and help drive decision-making
  • Partner to create data visualizations in Tableau, Shiny, and/or other dashboarding tools; assess initial validity and monitor accuracy of dashboards
  • Maintain knowledge based on the latest relevant scientific literature to identify and evaluate state-of-the-art methodologies and strengthen the team capabilities 
  • Support the development of educational materials for commercial activities
  • Other related duties as needed

More about You

  • Masters in Genetics or Bioinformatics or related degree in Life Sciences; MBA a plus 
  • 5 years of relevant experience in the biopharmaceutical industry focusing on translational research, genetic analyses
  • Clinical Experience with genetic variant interpretation in the context of the following:
    • ACMG (American College of Medical Genetics) classification required
    • Familiarity with genetic variant types and formats (e.g., HGVS) required,
    • Familiarity with data analyses of large genetic data sets required
    • Exposure to other types of data sets a plus
  • Ability to convey potentially complex and technical analysis in simple terms to non-technical audiences 
  • Must have ability and willingness to assess and interpret current therapeutic and pipeline assets data to support development of commercial deliverables, i.e., assessment of genetic variants in the context of market sizing and patient journey, educational assets proactively and strategically
  • Proficiency in using R/Python and experience in Unix/Linux environment  
  • Proficiency in Tableau, PowerBI, R Shiny, and/or other dashboarding tools strongly preferred
  • Ability to work with relational databases (SQL experience preferred)
  • Ability to work in a shared coding environment while adhering to best coding and software development practices in both development and production environments
  • Demonstrated ability to manage multiple complex projects and programs simultaneously  
  • Positive, open, and creative attitude with strong collaboration, interpersonal, and communication skills with cross-functional partners  
  • Ability to travel up to 15%

#LI-TG1

What Now?

We’re always looking for solution-oriented, critical thinkers.

So, if you’re comfortable with ambiguity and candor, relish challenging yourself, and place kindness and integrity at the forefront of how you approach your peers and work, then we encourage you to apply.
 

#LI-Remote

#LI-TG1

This position is remote. However, you will be expected to work on site at one of Sarepta's facilities in the United States and/or attend Company-sponsored in-person events from time to time.

The targeted salary range for this position is $132,000 - $165,000 per year. Sarepta is making a good faith effort to be transparent and accurate around our hiring ranges. The salary offer is commensurate with Sarepta’s compensation philosophy and considers factors including, but not limited to, education, training, experience, external market conditions, criticality of role, and internal equity.

Candidates must be authorized to work in the U.S.

Sarepta Therapeutics offers a competitive compensation and benefit package.

Sarepta Therapeutics is an Equal Opportunity/Affirmative Action employer and participates in e-Verify.

Salary : $132,000 - $165,000

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