Program Leader, SPT-300 Program

Seaport Therapeutics is seeking a talented Program Leader (PL) to be a strategic leader who is responsible for establishing the long-term vision and strategy, and achieving strong execution of the SPT-300 Program in order to maximize its future clinical and commercial success in the treatment of depression. The SPT-300 program is entering into a Phase 2 study and the PL will lead the program to execute the current plans within timelines/budget and to plan for potential future pivotal clinical studies, initial global regulatory filings and pre-commercial planning. He/she will provide leadership across the spectrum of drug development and pre-commercialization activities, ensuring achievement of program and corporate goals. The ideal candidate will be a strategic and entrepreneurial leader well-versed in drug development, and ideally commercialization, and a strong influencer who can integrate multiple perspectives effectively and align stakeholders across different functions and levels of the organization.

This position requires a presence in the Seaport area of Boston, with a strong preference for being onsite 3 – 4 days per week to foster collaboration and effective leadership as the SPT-300 program grows in complexity and importance. The role will report to the Chief Executive Officer (CEO).

Seaport Therapeutics has a proven strategy of advancing clinically validated mechanisms previously held back by limitations that are overcome with its proprietary GlyphTM technology platform. All the therapeutic candidates in its pipeline of first and best-in-class medicines are based on the Glyph platform, which is uniquely designed to enable oral bioavailability, bypass first-pass liver metabolism and reduce hepatotoxicity and other side effects. Seaport is led by an experienced team that was involved in inventing and advancing KarXT and other neuropsychiatric medicines and are guided by an extensive network of renowned scientists, clinicians and key opinion leaders across neurological specialties. For more information, please visit www.seaporttx.com

Summary Of Key Responsibilities

• Work collaboratively and cross-functionally with Research, Nonclincal Development, Clinical Operations, Clinical Research, Regulatory Affairs, Medical Affairs, Manufacturing, Quality Assurance, Drug Safety, Program Management, Distribution & Supply, Commercial and Finance to deliver on program goals within established timelines and budget.
• Oversee the development and execution of integrated, cross-functional strategic plans to develop, register and commercialize the program.
• Integrate cross-functional perspectives, ensuring that program strategy is informed by scientific evidence, clinical data, and the evolving competitive landscape. On an ongoing basis, proactively anticipate issues and ensure contingency plans are put in place; identify barriers and identify solutions to mitigate them; identify opportunities and strategies to capitalize on them.
• Working with functional leaders, ensure that appropriate prioritization and adequate resource allocation (financial and personnel) are present to meet the program timelines and deliverables.
• Maintain a high performing cross-functional program team, monitoring program resourcing, managing conflict, and building team culture; create a positive atmosphere to get the most out of the team.
• Serve as an internal and external ambassador for the program, fostering broad engagement to cultivate strategic KOL relationships and enabling overall integration of external insights to inform program strategies.
• Summarize and represent the program to Seaport leadership, Board of Directors, collaborators, and other external parties, as requested.
  
  

Qualifications

• BA/BS degree required; advanced medical, scientific or business degree strongly preferred.
• 12 - 15 years biopharmaceutical experience with previous program leadership responsibilities; demonstrated experience leading cross-functional teams in drug development and pre-commercialization.
• Deep understanding of drug development and global product registration is required, ideally in neuropsychiatry (with preference for preference for experience in depression or anxiety) and pre-commercialization and /or medical affairs considered a plus. Leadership of a recent successful program (positive pivotal data, regulatory approval, etc.) would be ideal.
• Proactive “hands-on” individual with collaborative orientation, who manages teams effectively, is very self-motivated and can smoothly establish strong working relationships within both internal and external organizations. Entrepreneurial problem solver. Achieves goals within timelines and budgets while anticipating and navigating obstacles effectively.
• Initiative and independence to identify short and long-term program needs, creatively formulate plans with team input, efficiently achieve timely decisions/alignment, and organize and deploy resources.
• Exceptional written and verbal communication skills; able to articulate program vision and motivate the team; communicates in an open, direct and timely manner; ensures broader organization is aligned with and aware of the program strategy, status and risks.
• Motivated by patient focus and personal commitment to high performance and results.
• Possesses high integrity and exceptional work ethic.