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Research Associate/Senior Research Associate, In Vivo Pharmacology

Seawolf Therapeutics, Inc.
San Diego, CA Full Time
POSTED ON 1/28/2025
AVAILABLE BEFORE 4/28/2025

Seawolf Therapeutics is a Series A genetic medicines company based in San Diego, CA. We are an innovative and collaborative team developing durable, redosable non-viral genetic medicines that will be first-in-class and best-in-class therapeutics for patients living with unmet medical needs. Come join our team and be an agent of change.

Overview of Role :

Seawolf Therapeutics is seeking an In Vivo Research Associate to join our in vivo pharmacology team. We are looking for a self-motivated individual for a primarily hands-on role, with about 80% of the work involving in vivo tasks with mouse models and 20% dedicated to data entry and experiment planning. This individual will be responsible for executing in vivo studies with non-viral delivery technologies in gene therapy applications. This position is cross-functional and collaborative, requiring regular interaction with all departments and presenting and discussing your work company-wide. The ideal candidate will possess the skills necessary to support day-to-day vivarium activities including planning, dosing animals, and sample collection in support of Seawolf’s research goals.

As the eyes of Seawolf in the vivarium, your observations and communication are crucial to our success. Effective communication, flexibility, and adaptability to last-minute, data-driven changes are essential. Proficiency and confidence in retro-orbital bleeds and IV injections are highly preferred.

We value a positive attitude, openness to feedback and training, and the ability to work under pressure in a fast-paced environment. If you can independently manage and prioritize multiple daily tasks, we would love to hear from you.

Qualifications :

Education and Experience :

  • Bachelor’s Degree
  • Minimum 1-2 years of experience in an animal facility setting

Technical Skills :

  • Expertise in rodent handling is required
  • Proficiency in retro-orbital bleeds and IV injections (highly preferred)
  • Ability to perform a wide range of in vivo procedures and practices is a plus
  • Experience with a range of WT and disease mouse models
  • Proficiency with Microsoft Suite programs (Excel, Word)
  • Organizational Skills :

  • Strong organizational skills and good data documentation
  • Ability to prioritize tasks
  • Strong attention to detail
  • Communication and Adaptability :

  • Ability to communicate effectively at all levels of the organization
  • Ability to adapt to changes in priority and / or studies
  • Ability to work in a fast-paced environment
  • Embraces the lean start-up mentality and is willing to wear multiple hats
  • Authorization :

  • All applicants must have authorization to work in the US
  • Responsibilities :

    Test Article Administration :

  • Administer test articles via various routes (IV, IP, SC, PO, HDD)
  • Blood Sample Collection :

  • Collect blood samples using Retro Orbital, Submandibular, and Saphenous methods
  • Animal Procedures :

  • Perform mouse euthanasia, perfusions, necropsies, and tissue harvest
  • Work with WT and disease mouse models
  • Study Support :

  • Conduct basic study support activities and clerical duties for In Vivo Pharmacology projects
  • Independently perform all methods and study types commonly used by the team
  • Understanding of IACUC foundation and guidelines in animal work
  • Animal Management :

  • Ear tag animals and update study logs
  • Regroup and sort mice based on study design
  • Measure and record mouse body weights
  • Euthanize animals as needed following standard operating procedures
  • Sample Handling :

  • Label tubes, centrifuge, and aliquot blood samples
  • Communication :

  • Communicate scheduling issues / changes to the In Vivo Pharmacology team and other departments
  • Present individual contributions in companywide meetings
  • The anticipated salary range for candidates who will work in San Diego, CA is $60,000 to $105,000 . The final salary offered to a successful candidate will be dependent on several factors that may include but are not limited to the type and length of experience within the job, type and length of experience within the industry, education, etc.

    Seawolf provides competitive salaries and an excellent benefits package including medical, dental, vision, life insurance, 401K, stock options and bonus.

    Salary : $60,000 - $105,000

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