Demo

Bioinformatics Data Scientist

Signature Science, LLC
Austin, TX Full Time
POSTED ON 3/10/2025
AVAILABLE BEFORE 6/4/2025

Job Description

Job Description

Position Purpose :

A bioinformatics data scientist is responsible for providing experimental design consulting and data analysis for large, high-throughput genomic experiments, with a focus on forensics and metagenomics. The bioinformatics data scientist will be responsible for designing and implementing annotated code for managing, manipulating, and analyzing large-scale genomic data, and for preparing thorough documentation and reporting.

This position can be located at any of our three locations, remote options as well.

Essential Duties and Responsibilities :

  • Develop tools for management, analysis and interpretation of high-density microarray and whole genome sequencing data.
  • Managing, manipulating, analyzing data using a combination of R, python, and UNIX tools.
  • Using established domain-specific open-source software and tools to manipulate and analyze genomic data.
  • Implement and execute data processing workflows and automated analytic pipelines.
  • Create standardized summary tables and figures using literate programming and reproducible workflows.
  • Conduct workflow benchmarking and documentation, identifying inconsistencies and resolving data problems.
  • Prepare SOPs, document source code / workflows, and write reports to summarize computational

requirements, processing status, and customized analysis results.

Required Knowledge, Skills & Abilities :

  • Expert proficiency working in a Unix / Linux environment.
  • Expert proficiency with R, RMarkdown, and the "tidyverse" tools for data analysis.
  • Advanced proficiency with open-source software, tools, and databases for analyzing next-generation sequencing data (whole-genome sequencing, RNA-seq, epigenetics, microbiome, and metagenomics).
  • Proficiency working with and developing using Docker and / or Singularity container technology.
  • Proficiency using version Control software (e.g., Git or similar) to manage programming code.
  • Proficiency with Python, Perl, or another scripting language.
  • Preferred : Experience with NextFlow, SnakeMake, or similar workflow / pipeline management systems.
  • Preferred : Familiarity with developing and querying relational databases.
  • Preferred : Familiarity with AWS and / or Azure cloud computing.
  • Education / Experience :

  • MS or PhD in Bioinformatics, Genomics, Data Science, or related field
  • Experience (5 years with MS or 3 years with PhD) managing and analyzing large-scale datasets produced sequencing platforms and deliver solutions for managing, visualizing, analyzing, and interpreting genomic data
  • Advanced experience using Linux / Unix text processing tools, R, and other open-source tooling to manipulate and format data, to assess data quality, and analyze data.
  • Clearance :

  • This position requires that the candidate be willing and able to complete a successful background screening for a security clearance. Candidates with a current security clearance will receive preference.
  • Supervisory Responsibilities :

  • May serve as a task / project lead.
  • Working Conditions / Equipment :

  • Ability to work in varying conditions to include : traditional office environments with sedentary extended periods required for code development and testing.
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