What are the responsibilities and job description for the Sr Research and Development III position at Software Galaxy Systems, LLC?
100% Onsite Cambridge, MA
40 hours per week
12 months w / possible extension
5-7 years of experience working with in vivo procedures, including injections (IV, SC, IP), blood collection and necropsy / tissue collection (brain, spinal cord, muscle and other tissues). Experience with in vivo immunization techniques for antibody generation. Ability to establish and perform biochemical and molecular assays, including ELISA / MSD, qPCR, BCA and other relevant techniques. Strong communication, organization and documentation skills. Quantitative data analysis using GraphPad Prism, MS Office or other relevant software.
We are seeking a Research and Development Associate III to join Antibody and Delivery Technologies unit within Biologics Drug Discovery (BDD) team, contributing to our mission to design, optimize, and develop therapeutics to improve the lives of patients with neurodegenerative diseases. In this role, you will work in a lab with a cross-functional team performing experiments where your work will support the development of novel biologics therapeutic approaches to treat CNS and neuromuscular diseases.
What You’ll Do :
- Establish and perform in vivo PK / PD studies for therapeutic proteins, antisense oligonucleotides, viral vectors and other modalities with CNS delivery / targeting properties.
- Perform in vivo immunizations to generate antigen specific antibodies from B cells by next-generation sequencing or hybridoma production
- Contribute to research efforts on specific projects involving novel BBB targets and other modalities
- Perform biochemical and molecular biology assays to enable PK / PD analysis of therapeutic candidate drugs, including ELISA / MSD, and qPCR
- Work as a part of a collaborative and cross-functional team
- Perform data analysis, maintain electronic laboratory notebooks, and present data
Qualifications : Required Skills :
Preferred Skills :
