What are the responsibilities and job description for the Senior Director, Biostatistics-Data Science-AI/ML position at Solid Biosciences?
Job Title
Sr. Director , Biostatistics – Data Science-AI/ML
Reports To
Chief Medical Officer
Date Updated
02/25/2025
Summary
The Sr. Director will be responsible for leading all statistical activities pertaining to Solid’s clinical development programs including clinical trial design, interim analyses, and analysis and reporting of cumulative and final clinical trial data. The Sr. Director will oversee outsourced routine statistical and data management activities as well as drive more sophisticated aspects of statistical strategy for the advancement of Solid’s clinical programs. In addition, the Director/Sr. Director may be called upon to provide statistical support to Solid’s non-clinical and translational projects as needed.
Key Duties & Accountabilities
Sr. Director , Biostatistics – Data Science-AI/ML
Reports To
Chief Medical Officer
Date Updated
02/25/2025
Summary
The Sr. Director will be responsible for leading all statistical activities pertaining to Solid’s clinical development programs including clinical trial design, interim analyses, and analysis and reporting of cumulative and final clinical trial data. The Sr. Director will oversee outsourced routine statistical and data management activities as well as drive more sophisticated aspects of statistical strategy for the advancement of Solid’s clinical programs. In addition, the Director/Sr. Director may be called upon to provide statistical support to Solid’s non-clinical and translational projects as needed.
Key Duties & Accountabilities
- Serve as in-house biostatistician for Solid’s clinical development programs
- Manage in-house biometrics team and outsourced biostatisticians/programmers
- Collaborate with in house computational Biologist/Geneticist around leveraging large data machine learning models of disease for both discovery and clinical development needs
- Perform trial statistician responsibilities including participation in study team meetings as needed, development of SAPs, reviewing shells and CRFs, design of early, mid and late-stage clinical trials, review of protocols/amendments, and conducting/supervising exploratory and ad hoc data analyses as appropriate
- Apply innovative statistical approaches to study design, data analysis, and use of external data sources
- Represent Solid/participate in collaborative external data-sharing consortia as needed
- Help establish and maintain appropriate Solid data standards, data review/oversight practices, and related SOPs in alignment with contract research partners
- Serve as a general clinical development and statistical resource
- May perform additional duties and ad hoc projects as required
- Excellent oral and written communication, presentation, and teaching skills
- Effective cross-functional collaborator
- Leadership
- Communication
- Degree in Biostatistics or related discipline with at least 5 years’ biopharmaceutical industry experience: BS with 12 years of related experience; MS with 8 years experience; or a PhD with 5 years experience.
- Experience with Bayesian methods and novel clinical trial designs preferred
- Facile with ML/AI driven analysis of large datasets
- Adept in the use of current statistical software
- Able to discuss and convey statistical concepts clearly to non-statistical colleagues
- Innovative, open-minded, and nimble thinker
- Able to work proactively and independently in a fast-paced, dynamic environment
- Located in Boston Metro area – preferred
- If remote, must commit to at least 5 hours online presence for normal working hours EST
- Occasional Travel ~ 10%
Salary : $249,000 - $300,000
