Demo

Director, Clinicogenomics Data Quality

Southern Research Institute
Birmingham, AL Full Time
POSTED ON 1/25/2025
AVAILABLE BEFORE 3/24/2025
Position: Director, Clinicogenomics Data Quality
Location: Birmingham, AL
Job Id: 4294
# of Openings: 1
Director, Clinicogenomics Data Quality (REMOTE)
General Summary
Southern Research (SR) is at a pivotal moment in its 84-year history. At the start of 2022, SR launched a new strategic plan focused on translational research in the life sciences. SR intends to invest over $150 million in this new strategy, including development of new facilities, platforms, and programs. We believe in the power of SR and our partners to unlock the immense potential of Alabama's biotech ecosystem to spur economic development, create jobs, and draw investment. Downtown Birmingham sees over $700M in extramural biomedical research every year, including over $300M from the NIH, in large part due to the contributions of Southern Research and the University of Alabama at Birmingham. We are on a mission to translate our R&D volume into investment, high-performance companies, and quality jobs in Alabama and in the Southeast United States.
The Director of Clinicogenomics Data Quality will report to the Chief Data Officer. The Director of Clinicogenomics Data Quality will be responsible for independent quality checks and assessments of genomic and clinical data sets collected through an Alabama State-wide initiative that provides access to clinical whole genome sequencing and facilitates sharing of patients' EMR/EHR data. The role will conduct clinicogenomic data management activities, including database specification, design, set-up, validation, quality assurance and implementation of data extraction procedures.
Essential Duties & Responsibilities
  • Serves as the SME in clinical genomic data analysis, ETL, management and engineering
  • Provides hands-on support towards building company's clinicogenomic data analytical platform
  • Designs, implements, and maintains databases to ensure accurate health information management
  • Designs, develops, evaluates, and deploys state-of-the-art analytical solutions to gain valuable data insights based on genomic, phenotypic, and clinical datasets
  • Evaluates, organizes, and manages company's valuable data assets
  • Designs cloud-based data model/schema to efficiently manage and query large scale genomic dataset
  • Supports both internal and external data requirements by leveraging AI/ML capabilities to keep up with the increasing demands of the business
  • Collaborates in a multidisciplinary and regulated clinical diagnostics environment with geneticists, bioinformaticians, software engineers, and IT infrastructure professionals
Requirements/Minimum Qualifications
  • Experience:
    • Hands-on experience in human genetics/multi-omics and clinical data analysis and software development
    • Hands-on experience in data ETL, data management, and data sharing for genomic and clinical applications
    • Hands-on experience with databases, including SQL and no-SQL
    • Hands-on experience with scripting language, such as Bash and Python
    • Hands-on experience in cloud platform (AWS) and commercial data platforms (datalake/warehouse such as Amazon Redshift / HealthOmics / HealthLake and Snowflake
  • Education:
    • Master's degree in Computer Science/Engineering, Biomedical Engineering, Bioinformatics, or related field; PhD degree preferred
    • 10 years of experience in healthcare IT, software development, or bioinformatics
    • Strong understanding of healthcare data standards (FHIR, HL7) and genomic data formats
    • Experience with cloud infrastructure, preferably AWS
    • Familiarity with HIPAA, Good Clinical Data Management Practice, and Computer Security
    • Excellent communication and leadership skills
Preferred Qualifications
  • Hands-on experience in clinical genotype and phenotype data analysis and modeling in the context of clinical trial design
  • Familiarity with commercial/open-source data analytical platforms
  • Familiarity with advanced data visualization techniques
  • Familiarity with clinical actionable variant interpretation and classification
  • DevOps experience such as unit testing, CI/CD is a plus.
  • Strong curiosity and the ability to learn quickly and adapt to a fast-changing environment
Core Values
Cultivating human connection - putting people first. We know that every individual makes a difference and that no one can do it alone. We believe the world's most powerful resource is human potential. We are an inclusive and courageous team where innovation and diversity of though go hand in hand. We understand that relationships move at the speed of trust.
Operating with precise execution - measuring what matters and owning results as a team. We leverage data to drive decisions that advance science. We recognize the importance of a stable foundation coupled with an agile mindset. We hold ourselves accountable and take pride in our work. We give and receive candid feedback as a gift that keeps us growing.
Harnessing relentless curiosity - our unstoppable, innovative force. We are driven to ask sharp questions and push the boundaries of knowledge. We use creativity and critical thinking as catalysts for finding solutions that change lives. We learn by doing, consistently striving to improve our relationships, training, methodologies, questions and results.
Stewarding a healthy community - implementing sustainable operations for a safe, engaging environment. We don't compromise on safety and health for our employees, customers or community. We believe a healthy community begins with inclusive economic opportunities. We respect the dignity of the patients we ultimately serve. We are motivated to serve communities that are underserved and markets that are overlooked.
Job Specific Behaviors
Strategic Decisionmaker - Obtains information and identifies key issues relevant to achieving a long-range goal; commits to a course of action after developing alternatives based on logical assumptions, facts, constraints, and resources.
Strategic Relationship Builder - Uses appropriate interpersonal styles to work effectively with others to meet mutual goals and objectives; understands the role & interrelationships of each organizational function; possesses skill in managing across functional and organizational lines.
Mission and Community Driven - Has an authentic desire to help steward Southern Research's culture, guard of our values, and champion our mission of innovation-driven economic development through translation of excellent scientific research.
Impactful Communicator - Expresses thoughts and ideas effectively in individual and group situations; adjusts language to the needs of the audience.
Results Oriented - Establishes stretch goals and manages to focus outcomes; demands excellence and demonstrates a strong commitment to organizational success; works to do what is best for all stakeholders.
Coaches / Develops Others - Uses appropriate interpersonal style to guide direct reports to action, create a sense of ownership, and encourage individuals to stretch beyond their own capabilities.
Inclusive - Holds a strong conviction that inclusion and innovation go together.
Highly collaborative - Cares less about who did it than how it got done; takes pride in shared outcomes and believes the whole is greater than the sum of the parts when it comes to team efforts.
Deeply curious - Recognizes that "innovation requires not knowing long enough to learn new things" and that "being actively open-minded involves searching for reasons why we might be wrong-not for reasons why we must be right-and revising our views based on what we learn."
Action oriented - Translates goals and objectives into actionable, metrics focused priorities and work streams for the team to execute.
Process Refiner - Observes details to continuously improve processes, looks for opportunities to create regular feedback loops to refine, and loves measuring what matters; strongly believes that "getting it right is more important than being right."
Physical Demands
  • Ability to work in an office setting using a computer for extended periods
  • Willingness to travel up to 4 times per year for conferences, client meetings, or on-site project work
Certifications, Licenses & Registrations
  • None required

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