Formulation Scientist

Job title: Formulation Scientist

Location: Cambridge, MA (02139) Onsite

Duration: 1 Year

This position's starting pay is: $26.64/hr.

Summary

• Technical Research & Development is seeking a highly motivated individual to join the discovery pharmaceutics function, Chemical and Pharmaceutical Profiling (CPP), and contribute to the development of discovery compounds.
• This successful candidate will join an energizing and collaborative research environment working as part of cross functional drug discovery teams in providing a developability assessment of new chemical entities.
• The ideal candidate must be capable of working independently to execute pre-formulation activities for small molecule and oligonucleotide drug candidates.
• As such, strong competency in physical pharmacy and preclinical formulation development is preferred to efficiently function in this role and in understanding the physicochemical properties of new chemical entities and implementing formulation strategies to maximize the exposure in preclinical in vivo studies.
• The candidate must demonstrate and foster strong team spirit and promote knowledge exchange within the group.
• Furthermore, the candidate should be able to proactively manage the interactions of simultaneous project related activities in support of multiple CPP Project Leads.
• In order to accomplish this, the role requires excellent time manangement and multitasking capacity, and timely communication of overall project information to the appropriate Project Lead via oral and written communication.

Key responsibilities

Your responsibilities include, but are not limited to:

• Design and develop stage appropriate, fit-for-purpose preclinical formulations. This includes development of both oral and parenteral formulations on a small scale

• Screening of solubility and dissolution rate enhancing formulations such as nanosuspensions and amorphous solid dispersions

• Assessment of the performance of prototype formulations using in vitro tests such as dissolution, precipitation behavior, and stability

• Basic drug substance characterization by techniques such as XRPD, DSC and TGA, DVS, PLM, DLS and UPLC. Assessment of the chemical and physical properties of small molecules, such as solubility, dissolution, particle size and chemical stability

• Preparation of formulations for use in preclinical in vivo studies and authoring protocols describing preparation of formulations for use at internal and external formulation labs

• Routine lab support such as buffer and mobile phase preparation, pH meter calibration, and basic troubleshooting of lab equipment. Shipping and receiving of samples between other client and external sites

What you’ll bring to the role:

• Ideally Master's degree with at least 1-3 years of experience. Or a Bachelor's degree with up to 3 years of any laboratory experience will be considered as well.

• Hands on experience with a range of analytical methods used to assess compound properties

• The ability to manage multiple parallel activities and deliver results on agreed timelines

• Ability to work independently but with good communication skills

Desirable requirements

• Prior experience communicating data and proposing further experimental work

• Practical experience in developing and preparing preclinical formulations

• Basic knowledge of physicochemical properties and their relationship to formulation development

About Us: Established in 2004, SPECTRAFORCE® is one of the largest and fastest-growing diversity-owned staffing firms in the US. The growth of our company is a direct result of our global client service delivery model that is powered by our state-of-the-art A.I. proprietary talent acquisition platform, robust ISO 9001:2015/ISO 27001 certified processes, and strong and passionate client engaged teams. We have built our business by providing talent and project-based solutions, including Contingent, Permanent, and Statement of Work (SOW) services to over 140 clients in the US, Canada, Puerto Rico, Costa Rica, and India. Key industries that we service include Technology, Financial Services, Life Sciences, Healthcare, Telecom, Retail, Utilities and Transportation. SPECTRAFORCE is built on a concept of “human connection,” defined by our branding attitude of NEWJOBPHORIA®, which is the excitement of bringing joy and freedom to the work lifestyle so our people and clients can reach their highest potential. Learn more at: http://www.spectraforce.com

Benefits: SPECTRAFORCE offers ACA compliant health benefits as well as dental, vision, accident, critical illness, voluntary life, and hospital indemnity insurances to eligible employees. Additional benefits offered to eligible employees include commuter benefits, 401K plan with matching, and a referral bonus program. SPECTRAFORCE provides unpaid leave as well as paid sick leave when required by law.

Equal Opportunity Employer: SPECTRAFORCE is an equal opportunity employer and does not discriminate against any employee or applicant for employment because of race, religion, color, sex, national origin, age, sexual orientation, gender identity, genetic information, disability or veteran status, or any other category protected by applicable federal, state, or local laws. Please contact Human Resources at LOA@spectraforce.com if you require reasonable accommodation.

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LA County, CA Applicant Notice: If you are selected for this position with SPECTRAFORCE, your offer is contingent upon the satisfactory completion of several requirements, including but not limited to, a criminal background check. We consider qualified applicants with arrest or conviction records for employment in accordance with all local ordinances and state laws, including the Los Angeles County Fair Chance Ordinance for Employers (FCO) and the California Fair Chance Act (FCA). The background check assessment will consider whether a criminal history could reasonably have a direct, adverse impact on the job-related safety, security, trust, regulatory compliance, or suitability for this role. Such findings may result in withdrawal of a conditional job offer.

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