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2025 SpringWorks Summer Intern - Structural Biology

SpringWorks Therapeutics
Durham, NC Intern
POSTED ON 4/10/2025
AVAILABLE BEFORE 5/5/2025

Job Description

Job Description

About SpringWorks Therapeutics :

SpringWorks is a commercial-stage biopharmaceutical company applying a precision medicine approach to developing and delivering life-changing medicines for people with severe rare diseases and cancer.

SpringWorks has a diversified targeted oncology pipeline spanning solid tumors and hematological cancers, including clinical trials in rare tumor types and highly prevalent, genetically defined cancers. SpringWorks' strategic approach and operational excellence in clinical development have enabled it to rapidly advance its lead product candidates into late-stage trials and enter into multiple collaborations with innovators in industry and academia to unlock the full potential for its portfolio and create more solutions for patients with cancer.

Your Role :

This internship provides a tremendous opportunity to gain daily, hands on experience in industrial science, while also contributing to SpringWorks' Structural Biology goals. The Intern will be mentored and work directly with members of the Drug Discovery Structural Biology team and will get experience with a variety of activities, including protein expression and purification, biophysical assays and crystallization of some of our discovery protein targets. The selected intern will have abundant and daily mentored opportunities to contribute to these important and required drug discovery activities.

Location Classification – Lab-Based : ​

This role will be required to work on site 5 days a week as the majority of the work will be conducted in our laboratory facility.. #LI-Onsite

Essential Duties and Responsibilities :

  • Prepare cell cultures of cloned constructs and perform scaled up expression
  • Harvest cell cultures, prepare cell lysates and purify proteins
  • Use state of the art platforms to perform biophysical or biochemical assays
  • Use state of the art lab automation to crystallize proteins
  • Have a great opportunity to experience industrial life science research
  • Engage fellow SpringWorkers and discuss and examine career paths
  • Perform other duties and responsibilities as assigned

Role Requirements :

  • Education : Candidates pursuing biology, chemistry, biochemistry or biophysics program degrees are encouraged to apply. Preferred applicants will be rising seniors, first year graduate students or stand out rising juniors from an accredited U.S. college or university before beginning the internship
  • Applicants should have at least completed core science and some upper-level classroom and laboratory course work in molecular biology, organic chemistry, biochemistry and related science and math courses
  • Candidates equipped with the necessary science classroom and bench skills will enjoy a more complete and highly immersive internship
  • Applicant has accrued upper-level classroom hours and developed some wet laboratory skills
  • Candidate has a good understanding and working knowledge of cell and molecular biology, cloning, cell culture, organic and biochemistry and chemical calculations
  • Excellent written, oral communication skills
  • Ability to communicate and collaborate with peers on a technical level
  • Effective organizational and interpersonal skills
  • Ability to manage and complete several ongoing tasks
  • Complete the assigned Capstone Project that is built around the essential duties and responsibilities
  • Present the Capstone Project to the research staff towards the end of the internship
  • Standard Requirements for all intern positions :

  • Ability to complete the entire 10-week program (from June 2, 2025 to August 8, 2025) and commit to 40 hours per week
  • Applicants must be available to work onsite weekly a minimum of 2 days / 5 days for onsite positions.
  • Final presentation to manager & department team members at the end of the 10-week program (mandatory).
  • Applicants must be at least 18 years of age at the start of the program.
  • Applicants currently enrolled in an accredited college / university for undergraduate, graduate or PharmD program. Must have completed at least two semesters at an accredited U.S. college or university before the start of the program.
  • Applicants must attend a school in a U.S. state or territory and be eligible to work in the United States.
  • Applicants must have a strong desire to pursue a career in a pharmaceutical or biotechnology field post-graduation.
  • Applicants must meet the minimum requirements of the role, both in Education (BS / MS / PharmD / Ph.D / etc.) and experience.
  • Applicants must have a minimum 3.0 GPA (on a 4.0 scale)
  • Compensation & Benefits :

    The expected hourly rate for this position is $29.00 / hour.

    We offer best-in-class benefits for our team of SpringWorkers who work with urgency on behalf of patients suffering from devastating diseases. Interested in learning more, review additional information here Benefits.

    DE&I :

    We believe in fostering a culture of belonging. Explore how we are committed to DE&I

    EEO Statement :

    SpringWorks maintains an EEO Policy providing for equitable opportunities for employment and conditions of employment to all employees and applicants regardless of actual or perceived sex (including pregnancy, childbirth, breastfeeding or related medical conditions), gender, gender identity or gender expression, sexual orientation, partnership status, marital status, familial status, pregnancy status, race, color, national origin, ancestry, caste, religion, religious creed, age, alienage or citizenship status, veteran status, military status, physical or mental disability, past or present history of mental disorder, medical condition, AIDS / HIV status, sickle cell or hemoglobin C trait, genetic predisposition, genetic information, protected medical leaves, victims of domestic violence, stalking, or sex offense, political affiliation and any and all other characteristics or categories protected by applicable federal, state or local laws. SpringWorks treats all employees and applicants fairly in the selection process (and in other personnel activities) by giving all employees and applicants the same opportunities for employment. SpringWorks' Equal Employment Opportunity Policy is intended to ensure that there are no barriers that would prevent members of a protected group from a fair and equitable opportunity to be hired, promoted, or to otherwise take advantage of employment opportunities.

    This Equal Employment Opportunity Policy applies to all aspects of employment, including, without limitation, recruitment, hiring, placement, job assignment, promotion, termination, transfer, leaves of absence, compensation, discipline, and access to benefits and training. Any violation of this Policy will result in disciplinary action up to and including termination of employment.

    Privacy :

    Upon submission of this form I understand that SpringWorks Therapeutics is based in the United States and personal data submitted in the form will be transferred and accessed in the U.S.. Information about SpringWorks Therapeutics' privacy practices can be found at Privacy Policy - Springworks (springworkstx.com).

    Salary : $29

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