What are the responsibilities and job description for the Upstream Process Manufacturing Associate, Mammalian position at STC Biologics Inc?
Job Title: Upstream Process Manufacturing Associate focusing on Production in CHO cells
Location: Newton, MA
Company: STC Biologics, Inc
Job Type:Full-Time
Experience Level:Mid to Senior (5-10 years relevant experience)
About Us:
STC Biologics is a biologics Contract Development and Manufacturing Organization (CDMO) specializing in the production and development of biologics. Our facility in Newton, MA, is equipped with state-of-the-art technology and a dedicated team committed to excellence, innovation, and quality in the biopharmaceutical industry. We seek motivated individuals eager to contribute to our mission of producing high quality innovative products.
Job Description
The Upstream Process Manufacturing Associate will be responsible for executing and optimizing upstream manufacturing processes for biologics production up to 500-1000L scale. The candidate will have extensive experience with fed batch culture using Thermo HyPerforma Bioreactors and Delta V and will play a pivotal role in ensuring efficient and compliant manufacturing operations.
Key Responsibilities:
- Execute and optimize upstream process operations, focusing on cell culture activities including media preparation, seed train, bioreactor seeding and harvest.
- Monitor and analyze process parameters, troubleshoot the operational issues to maintain a high standard of product quality.
- Collaborate with cross-functional teams, including Quality Assurance, Quality Control, and Development, to support technology transfer and process scale-up activities.
- Ensure adherence to cGMP regulations and company SOPs, maintaining meticulous documentation and records for process operations.
- Participate in root cause analysis and continuous improvement initiatives to enhance process robustness.
- Train and mentor junior staff, fostering an environment of learning and professional development.
Qualifications:
- Bachelor’s in Biotechnology, Biochemistry, Chemical Engineering, or a related field.
- 5-10 years of experience in upstream biologics manufacturing within a CDMO or similar environment.
- Proficient knowledge and hands-on experience with Thermo HyPerforma System or equivalent and other upstream technologies.
- Strong understanding and experience with cell culture techniques, bioreactor operations, and fermentation processes.
- Demonstrated experience with cGMP compliance and documentation practices.
- Excellent interpersonal skills with the ability to collaborate effectively in a team-oriented environment.
- Strong analytical and problem-solving skills, with attention to detail.
- Flexibility to work in a fast-paced, innovative, and dynamic work environment.
Benefits:
- Competitive salary and bonus opportunities.
- Health, dental, and vision insurance.
- Retirement savings plan
- 4 week paid time off and additional holidays.
- Professional development opportunities.
Application Process:
Interested candidates should submit a resume highlighting their relevant experience and interest in the role.
Join STC Biologics and play a key role in advancing biopharmaceutical manufacturing and improving patient outcomes worldwide. Apply today to become part of our innovative team!