Co-op, mRNA Process Development

Company Overview:

Strand Therapeutics is a clinical stage biotechnology company utilizing synthetic biology to genetically program mRNA to deliver truly revolutionary immunotherapies to patients.

Building on the idea of creating smart therapies based on Boolean logic circuits, Strand was started by biological engineers working together at MIT who were seeking to apply the concept of the emerging field of mRNA therapeutics. Strand's technology is therapeutic-area and mRNA modality agnostic where therapeutic proteins are encoded onto modified, self-replicating, or circular mRNA backbones which in turn are programmed with cell-specific sensors and circuits.

Today, Strand has established three platforms with one clinical stage asset and several programs in preclinical development as well as early discovery. Our lead program, STX-001, is currently being evaluated in a phase 1 clinical trial for solid tumors. Our corporate headquarters is located in the Fenway district of Boston, Massachusetts.

Become the next standout single strand!

Job Summary:

Strand is looking for people who have the enthusiasm and motivation to be a highly contributing member of a small but extremely productive team. This opportunity will offer the employee the ability to work in a matrix-based environment and be a part of the future strategy of the company.

We are looking for a Co-op, mRNA Process Development to join the Technical Operations team at Strand Therapeutics. The incoming co-op will work within the Process Development group to help advance our platform for the manufacturing and process optimization of high quality mRNA therapeutics. The candidate will be expected to work in an innovative, fast-paced, and collaborative biotech environment.

Primary Responsibilities:

• Execution of experiments related to the advancement of Strands mRNA manufacturing and/or process optimization platforms.
• Carrying out the production and characterization of IVT synthesized mRNA.
• Support screening, optimization, and scale-up efforts for enzymatic reactions, chromatographic separations and filtration processes - including ultrafiltration, diafiltration, and sterile filtration.
• Working across diverse areas to support the group's development activities in a fast-paced and collaborative environment.
  
  

Qualifications:

• On track to graduate with a B.S. or M.S. in Biochemistry, Chemical Engineering, Molecular Biology, Bioengineering, Molecular Medicine, Genetics or related field. Experience in the biotechnology space is a plus.
• mRNA working experience is strongly preferred, but not a requirement.
• Basic knowledge of chromatographic purification and filtration methods for biologics.
• Experience with standard biological analytical methods (gel electrophoresis, ELISA, UV-Vis spectroscopy, etc.).
• Ability to follow standard operating procedures, make careful observations, maintain clear and complete records of lab work.‪
• Strong collaboration and inter-personal skills. Ability to present scientific context, experimental set up, data interpretation, and big-picture conclusions to a diverse audience.
  
  

Strand Therapeutics is an equal opportunity employer. We do not discriminate on the basis of race, color, gender, gender identity, sexual orientation, age, religion, national or ethnic origin, disability, protected veteran status or any other basis protected by applicable law. Strand does not accept unsolicited resumes from any source other than directly from candidates.

Job Type: Intern

Salary: Commensurate with role and experience