Demo

Research Associate III

Tailored Management
South San Francisco, CA Full Time
POSTED ON 1/22/2025
AVAILABLE BEFORE 4/20/2025

This position is in the Investigative Toxicology Group within the department of Safety Assessment in

  • s Research and Early Development organization. The mission of the Investigative Toxicology group is to elucidate the mechanisms underlying toxicities that are observed non-clinically and / or in clinical trials through hypothesis driven research. This process involves closely collaborating with scientists across the organization to support the overall safety assessment for our Client therapeutics spanning drug discovery through clinical development and marketing. The group provides fit-for-purpose wet lab-based investigation to address target safety assessment, lead optimization, and issue mitigation by employing state-of-the-science in vitro and ex vivo approaches. As such, we are constantly establishing new platforms and technologies to support a constantly changing portfolio, Client modalities, and emerging therapeutic area needs. We are looking for a highly motivated candidate to work in collaboration with other researchers in the Investigative Toxicology lab. This individual must have experience in cell culture and will be responsible for : culturing and expanding primary cells and cell lines for in vitro screenings, treating and performing assays to assess cytotoxicity and metabolic changes of cells, capturing cell culture images using confocal and high content imaging. This individual will be working with cells from a broad range of tissues (liver, GI, vascular, ocular) and is expected to make detailed observations related to experiments, perform, analyze data, and interpret results. He / she will contribute with scientific insights and also work in projects related to peer review publications. The individual will also participate in projects related to the development of microfluidics platforms to support toxicity testing for our drug discovery program.

Job Description

  • has an open Scientific Researcher position in the Investigative Toxicology group within the department of Safety Assessment located in our South San Francisco campus. The Investigative Toxicology group's goal is to use ex vivo and in vitro tools to assess safety liabilities and mechanisms of toxicity observed pre-clinically to support the entire portfolio spanning discovery through development. This laboratory-based role involves performing, qualifying and implementing biological assays and technologies to support the Investigative Toxicology group. They will also contribute to ongoing efforts to understand the impact of complex-in-vitro models in hazard id and liability assessment. This is an ideal position for a researcher who is enthusiastic about learning and contributing to projects with a broad range of techniques. As such the position requires excellent communication and collaboration skills, a desire to learn about and integrate multiple aspects of drug toxicity, and a passion for lab-based research. In particular a candidate who will be successful in this role will be able to collaborate with subject matter experts to collaboratively design a scope of work and key performance indicators for a research project, but then independently drive forward the experimental work including towards identified milestones. Additionally, the success in this role will require flexibility and a willingness to learn new model systems as well as initiative to troubleshoot unexpected experimental results or limitations.
  • Skills :

  • Candidate will provide scientific and technical support to assays and platforms supported or under development by the Investigative Toxicology group by :
  • Performing experiments involving : immortalized and primary cell culture, cell viability assessment, ELISAs, gene expression analysis, high content screening, confocal microscopy, and flow cytometry. Experience with these methodologies is desirable, but not required.
  • A large portion of the cell culture work conducted will focus on the use of organoid or other complex in-vitro model (CIVM) systems
  • Maintaining documentation related to protocol execution and results.
  • Writing protocols and contributing to final reports as appropriate.
  • Adhering to departmental SOPs to ensure study integrity and quality.
  • Conducting experiments with a high level of independence and initiative.
  • Performing tasks with minimal direct supervision for routine methods and studies commonly employed by the team.
  • Education :

  • Bachelors (BS / BA) in pharmacology, pharmaceutical science, biology, bioengineering, chemistry, physiology, or related discipline is required; Masters (MS) degree is desirable, but not required.
  • Technical Experience Requirements :

  • 1-3 years of laboratory experience with hypothesis-driven research.
  • Ability to analyze, integrate, and present data in a presentation is required.
  • Experience with immortalized and / or primary cell culture, cell viability assessment, ELISAs, gene expression analysis, high content screening, confocal microscopy, and flow cytometry is highly desired.
  • Experience with complex in-vitro model systems is highly desired.
  • Second Job Title :

  • Scientific Researcher, Investigative Toxicology
  • Role will Involve :

  • Sitting or standing for extended periods.
  • Performing repetitive tasks such as cell culture, pipetting and labeling tubes.
  • Collaboration across the Investigative Toxicology team and with key stakeholders.
  • Work with potentially hazardous materials including (but not limited to) : chemotherapeutics, biological hazards, and human primary cells.
  • If your compensation planning software is too rigid to deploy winning incentive strategies, it’s time to find an adaptable solution. Compensation Planning
    Enhance your organization's compensation strategy with salary data sets that HR and team managers can use to pay your staff right. Surveys & Data Sets

    What is the career path for a Research Associate III?

    Sign up to receive alerts about other jobs on the Research Associate III career path by checking the boxes next to the positions that interest you.
    Income Estimation: 
    $102,775 - $137,396
    Income Estimation: 
    $153,127 - $203,425
    Income Estimation: 
    $139,626 - $193,276
    Income Estimation: 
    $164,650 - $211,440
    Income Estimation: 
    $130,030 - $173,363
    Income Estimation: 
    $82,813 - $108,410
    Income Estimation: 
    $120,989 - $162,093
    Income Estimation: 
    $74,806 - $91,633
    Income Estimation: 
    $71,928 - $87,026
    Income Estimation: 
    $145,337 - $174,569
    Income Estimation: 
    $102,775 - $137,396
    Income Estimation: 
    $153,127 - $203,425
    Income Estimation: 
    $139,626 - $193,276
    Income Estimation: 
    $164,650 - $211,440
    Income Estimation: 
    $130,030 - $173,363
    Income Estimation: 
    $130,030 - $173,363
    Income Estimation: 
    $194,895 - $259,743
    Income Estimation: 
    $192,057 - $260,440
    Income Estimation: 
    $249,515 - $311,938
    Income Estimation: 
    $155,477 - $213,492
    Income Estimation: 
    $68,606 - $89,684
    Income Estimation: 
    $88,975 - $120,741
    Income Estimation: 
    $68,121 - $81,836
    Income Estimation: 
    $71,928 - $87,026
    Income Estimation: 
    $125,958 - $157,570
    View Core, Job Family, and Industry Job Skills and Competency Data for more than 15,000 Job Titles Skills Library

    Job openings at Tailored Management

    Tailored Management
    Hired Organization Address Madison, WI Contractor
    Join a leading customer experience platform that empowers businesses to build stronger relationships by streamlining sup...
    Tailored Management
    Hired Organization Address Nashville, TN Full Time
    Position : Manager, eCommerce & Artist Services Location : Nashville, TN 7 Months (Possibility of Extension) Pay rate : ...
    Tailored Management
    Hired Organization Address New York, NY Full Time
    Job Description : Research Technology Project Manager US - Remote, East Coast Preferred Responsibilities Collaborate Res...
    Tailored Management
    Hired Organization Address New York, NY Full Time
    Job Description : True Title : Technology Analyst Max BR Hourly, Remote, but EST time zone only Technology Analyst with ...

    Not the job you're looking for? Here are some other Research Associate III jobs in the South San Francisco, CA area that may be a better fit.

    Staff Research Associate III

    University of California - San Francisco Campus and Health, San Francisco, CA

    Staff Research Associate III

    NCIRE, San Francisco, CA

    AI Assistant is available now!

    Feel free to start your new journey!