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Staff Scientist, Bioinformatics (NGS)

Takara Bio USA, Inc.
San Jose, CA Full Time
POSTED ON 3/1/2025
AVAILABLE BEFORE 5/29/2025

Job Title : Staff Scientist, Bioinformatics (NGS)

Reports to : R&D Group Leader, Bioinformatics

FLSA Class : Exempt

Learn more about our company and how we support you :

Takara Bio USA (TBUSA) empowers life science discovery. We bring innovation and inspiration to every scientist - promoting discoveries that improve health and the environment. We hold values that all employees and prospective candidates should demonstrate : Innovation, Teamwork, Integrity, Respect, Growth, Diversity and Quality. We value helping employees develop their skills and you will be part of this journey!

At Takara Bio, we know that every experimental decision has an impact. Choices matter, from design to data analysis. We create best-in-class products that get the job done. In your hands, what do those research reagents and kits create? Something powerful : knowledge, understanding, and-often-hope! Together we can improve the human condition through biotechnology...and That's Good Science!

How this role drives the company forward :

The Staff Scientist, Bioinformatics is responsible for collecting product requirements and designing and developing NGS analysis pipelines to meet those requirements. The Staff Scientist, Bioinformatics is responsible for all aspects of the software development process from the project initiation to software release, including supporting internal and external customer bioinformatics requests.

The Staff Scientist, Bioinformatics role is office-based.

Approximately 5% travel, including overnight, is required.

How you will make an impact :

As a Staff Scientist, Bioinformatics, you will be part of a growing team of bioinformaticians primarily focused on single-cell and bulk RNA, DNA, and immune profiling NGS applications.

You will support R&D with analysis and pipeline development while using and promoting best practices for coding (Python / R) and reproducible research. You will develop interactive data visualization resources that enable robust biomarker discovery and guide the user to relevant biological insights. You excel at interpreting results and troubleshooting tools, analyses, and code. You have a deep understanding of factors important to NGS experiments and analyses and are interested in understanding the algorithms and parameters of bioinformatic tools.

The ideal candidate will have extensive hands-on experience with (1) analyzing and interpreting immune repertoire profiling results, (2) using advanced single-cell RNA analysis techniques, and (3) creating customer-facing R Shiny applications and Nextflow-based workflows.

What will you do :

  • Works to develop bioinformatics packages / pipelines for one or more projects, exhibiting good code design and development practice.
  • Analyzes NGS data and generates reports exhibiting good analytical design, data summary and interpretation, and clear report preparation.
  • Works closely and independently, through regular communication, with Product Managers and senior members of the Bioinformatics and R&D teams to understand market trends and competition relevant to products worked on. Proposes new tools for development based on this analysis and works independently with Product Managers and / or R&D to design appropriate specifications.
  • Develops and releases new bioinformatics tools and pipelines according to approved proposals and within stated deadlines.
  • Follows standard Software Development Life Cycle process, including version control and independently authors related technical documentation.
  • Serves as a resource to R&D and other departments within the organization, including Product Management, Quality Control, and Quality Assurance especially during product development and release.
  • Represents R&D at scientific meetings or in front of customers, including presenting seminars or tutorials on tools they have developed.
  • Serves to support Sales and Technical Support representatives on technical matters.
  • This position does not have supervisory responsibilities.

How will you get here?

  • Typically requires a Ph.D. in Bioinformatics or a relevant scientific discipline followed by a minimum of 5 to 8 years post-Ph.D. experience in Bioinformatics working in academia or industry.
  • Experience in pipeline design and development following standard Software Development Life Cycle practice, including developing appropriate wrappers to provide easy-to-use tools for non-Bioinformaticians.
  • Extensive experience analyzing NGS data sets using industry-standard methods and tools.
  • Professional pipeline development experience with one or more major programming languages such as Python or R under a Linux environment is required.
  • Strong statistical, mathematical and / or analytical skills as demonstrated by experience with R or Python data science libraries.
  • Collaborative personality with strong interpersonal skills.
  • Excellent oral and written communication skills.
  • AAP / EEO Statement :

    Takara Bio USA, Inc. does not discriminate in employment on the basis of race, color, religion, sex (including pregnancy and gender identity), national origin, political affiliation, sexual orientation, marital status, disability, genetic information, age, membership in an employee organization, retaliation, parental status, military service, or other non-merit factors.

    Additional Information about the role :

    Please note this job description may not cover or contain a comprehensive listing of activities, duties or responsibilities that are required of the employee for this job. Duties, responsibilities and activities may change at any time with or without notice. The US base salary range for this full-time position, expected to be located in San Jose, CA, is $155,000 - $165,000 USD. This range may be modified at any time at our sole discretion. This base salary does not include additional bonus compensation and benefits. Learn more about benefits at https : / / www.takarabio.com / about / careers / company-benefits. Individual compensation packages are based on factors unique to each candidate, including job-related skills, training, experience, qualifications, work location, and market conditions.

    Salary : $155,000 - $165,000

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