Principal Analyst, Chemical Informatics (Apply in minutes)

By clicking the “Apply” button, I understand that my employment applicationprocess with Takeda will commence and that the information I provide in myapplication will be processed in line with Takeda’s (PrivacyNotice)(https : urldefense.proofpoint.comv2url?u=https-3A__www.takedajobs.com_privacynotice&d=DwMFAg&c=eIGjsITfXP_y-DLLX0uEHXJvU8nOHrUK8IrwNKOtkVU&r=R7Z8seTzCwqpIAi7APe73INoZm9-sxCdHQKjwfWPCQs&m=dHDH9k7lo2jkh-wOGxeg4p4mAfV8Vr_FCuR60MDlbTo&s=Tj67ufwJLuB1vZlHjecELumJYbWpaHHiC9kI2nnRDKU&e=)and (Terms ofUse)(https : urldefense.proofpoint.comv2url?u=https-3A__www.takeda.com_terms-2Dof-2Duse_&d=DwMFAg&c=eIGjsITfXP_y-DLLX0uEHXJvU8nOHrUK8IrwNKOtkVU&r=R7Z8seTzCwqpIAi7APe73INoZm9-sxCdHQKjwfWPCQs&m=dHDH9k7lo2jkh-wOGxeg4p4mAfV8Vr_FCuR60MDlbTo&s=_CIJE9CeroUy1ZLHeCKCoxM1jCAPZSz9Vq5yEGoRCGg&e=).I further attest that all information I submit in my employment application istrue to the best of my knowledge.##

• Job Description
• Job Posting DescriptionAt Takeda, we are a forward-looking, world-class R&D; organization thatunlocks innovation and delivers transformative therapies to patients. Byfocusing R&D; efforts on three therapeutic areas and other targetedinvestments, we push the boundaries of what is possible to bring life-changingtherapies to patients worldwide.
• Objective Purpose :
• Work as part of a multi-disciplinary team of medicinal chemists, structural biologists, data scientists and biologists and provide computational expertise to advance drug discovery projects
• Contribute to drug discovery efforts across various modalities including small molecules, PROTACs, RNA inhibitors, peptides, and more
• Implement and execute innovative computational methodologies and tools such as AI, free energy, and cheminformatics approaches to support drug discovery efforts
• Accountabilities :
• Demonstrate an understanding of computational chemistry principles and their application within a multidisciplinary drug discovery environment.
• Independently design, develop and execute research assignments, contributing to multiple projects
• Identify, develop, validate, and implement innovative computational approaches that enhance research productivity and success
• Provide key technical knowledge and input to project teams to drive decision-making in drug discovery projects
• TechnicalFunctional (Line) Expertise :
• Experience with a variety of computational tools and methodology including large-scale virtual screening, ligand ability analyses, homology modeling, quantum mechanics, pharmacophore elucidation, machine learning and more against common drug discovery targets (GPCRs, Kinases etc.)
• Comprehensive experience in data mining and data analysis.
• Familiarity with organic and synthetic chemistry concepts
• Demonstrated ability to provide project teams with computational strategies to inform, influence, and prioritize designs for potencyselectivity and improve ADMETox endpoints
• Experience developing and deploying design andor AI platforms to impact drug discovery
• Familiarity with standard computational chemistry software including Schrodinger Suites,_ KNIME, and more
• Proficiency in scientific scripting and programming languages including python
• Experience with operations in Linux andor cloud environments
• Leadership :
• Identifies, plans and executes novel scientific projects and lead platform initiatives.
• Decision-making and Autonomy :
• Independently manages workload and expectations
• Scientifically independent
• Influence decision making within the department
• Lead a computational chemistry initiative such as holo structure prediction, ligandability analyses, and large-scale virtual screening workflows
• Interaction :
• Conducts scientific presentations to internal audiences
• Collaborate with cross functional scientists and across geographic areas
• Innovation :
• Maintain an interest in cutting-edge science and act proactively to acquire technologies that match the needs of the team
• Receives high level instructions on all work, determines methods on new assignments, works closely with manager
• EDUCATION, BEHAVIORAL COMPETENCIES AND SKILLS :
• PhD degree in Chemistry or equivalent
• Expected 2 years of experience in industry
• Maintain an interest in cutting-edge science and act proactively to acquire technologies that match the needs of the team
• Takeda Compensation and Benefits Summary
• We understand compensation is an important factor as you consider the nextstep in your career. We are committed to equitable pay for all employees, andwe strive to be more transparent with our pay practices.
• For Location :
• Boston, MA
• U.S. Base Salary Range :
• 133,000.00 - 209,000.00The estimated salary range reflects an anticipated range for this position.The actual base salary offered may depend on a variety of factors, includingthe qualifications of the individual applicant for the position, years ofrelevant experience, specific and unique skills, level of education attained,certifications or other professional licenses held, and the location in whichthe applicant lives andor from which they will be performing the job. Theactual base salary offered will be in accordance with state or local minimumwage requirements for the job location.U.S. based employees may be eligible for short-term and or long-termincentives. U.S. based employees may be eligible to participate in medical,dental, vision insurance, a 401(k) plan and company match, short-term andlong-term disability coverage, basic life insurance, a tuition reimbursementprogram, paid volunteer time off, company holidays, and well-being benefits,among others. U.S. based employees are also eligible to receive, per calendaryear, up to 80 hours of sick time, and new hires are eligible to accrue up to120 hours of paid vacation.
• EEO Statement_
• Takeda is proud in its commitment to creating a diverse workforce andproviding equal employment opportunities to all employees and applicants foremployment without regard to race, color, religion, sex, sexual orientation,gender identity, gender expression, parental status, national origin, age,disability, citizenship status, genetic information or characteristics,marital status, status as a Vietnam era veteran, special disabled veteran, orother protected veteran in accordance with applicable federal, state and locallaws, and any other characteristic protected by law._##
• Locations
• Boston, MA##
• Worker Type
• Employee##
• Worker Sub-Type
• Regular##
• Time Type
• Full time
• Job Exempt