2025 U.S Summer Internship Program: High-plex Spatial Transcriptomics Biomarker Assay Development

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Job Description

Takeda has been translating science into breakthrough medicines for 240 years. Every step of the way, our teams have worked together to tackle some of the most challenging problems in drug discovery and development. Today, we’re a driving force behind innovative therapies that make a lasting difference to millions of patients around the world.

In R&D, all of our history and potential comes together in an environment that welcomes diversity of thought and amplifies every voice. Working closely with colleagues, you’ll play a key role in bringing our rich pipeline of products forward to help patients. Come join a team that’s earned trust for more than two centuries, and find out how advancing transformative therapies at Takeda will shape your bright future.

Autoimmune diseases are a group of diverse diseases with a common cause in which the immune system responds to self-antigens, leading to damage or dysfunction of tissues. Biomarkers are measurable substances in the body associated with the intensity of a disease or other physiological states. They can be used in the diagnosis, prognosis, and treatment of different diseases. The summer internship project aims to :

• Use clinical samples of autoimmune diseases with respective control group samples
• Screen for miRNA, mRNA, and Protein biomarkers using high-plex multi-omics spatial transcriptomics platforms to identify disease-specific or common autoimmune biomarkers
• Use the NanoString nCounter platform to identify miRNA biomarker candidates in clinical serum samples of autoimmune disease patients. This platform uses a unique barcode system and can directly detect up to 799 target genes in a single sample without amplification. FFPE or freshly frozen tissue samples will be used for the spatial transcriptomic analysis. By unraveling the transcriptomic biomarkers at miRNA, RNA, and protein levels, the project aims to understand the disease-specific biomarkers of autoimmune diseases at the transcription and translational levels.
• The intern will be involved in

Sample processing, reagent preparation, reaction setup, instrumentation learning, and data analysis for the nCounter and spatial transcriptomic platforms

Internship Development Opportunities :

Job Requirements :

Internship Eligibility

The intern must be able to commit to one of these time frames

Program Highlights :

Applications will be accepted between January 6th and January 31st

Takeda Compensation and Benefits Summary

We understand compensation may bean important factor as you consider an internship opportunity. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.

For Location :

USA - MA - Cambridge - Binney St

U.S. Hourly Wage Range :

21.00 - $46.00

The estimated hourly range reflects an anticipated range for this position. The actual hourly wage offered will depend on the candidate’s school year / level to be entered following completion of internship.The actual hourly wage offered will be in accordance with state or local minimum wage requirements for the job location.

U.S. internship benefits vary by location and may include :

Paid sick time

Civic Duty paid time off

Participation at company volunteer events

Participation at company sponsored special events

Access to on-site fitness center (where available)

Commuter Benefit : To offset your work-commute expenses, Takeda provides U.S. employees with a fixed monthly subsidy to be used for either public transportation (transit) or parking.

EEO Statement

Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.

Locations USA - MA - Cambridge - Binney St

Worker Type Employee

Worker Sub-Type Paid Intern (Fixed Term) (Trainee)

Time Type Full time

Job Exempt

Salary : $21 - $46