What are the responsibilities and job description for the Research Senior Scientist -Antibody engineering position at Takeda?
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Job Description
Objective / Purpose :
- A new position within the Biologics Engineering & Antibody Discovery team of Global Biologics, this role requires an experienced, self-motivated and driven scientist who can positively impact the pipeline through engineering and optimization of therapeutic candidates from in vitro and in vivo platforms, while working closely with the ML / computational team.
- Depth of understanding of antibody engineering for design, optimization, and engineering utilizing structure-function relationships and molecular modelling while predicting behaviors.
- Design and execution of optimization of molecules for properties such as affinity, potency, stability, specificity, stability, PK. May work on multiple programs in parallel. Formats to include monoclonal, single domain antibodies (VHH, VH), and multispecific antibodies. Deep understanding of antibody structure and function, as well as biologics discovery processes.
- Effective communication with the NGS and computational teams to best optimize
- The role requires excellent technical knowledge of antibody engineering and coding using python and optimization tools
- A critical element of the role is recognizing and streamlining the most efficient ways of working. The role requires tremendous drive, and motivation to deliver (and beat) team and program goals, while also pushing the boundaries to enhance discovery and optimization.
- Analysis, interpretation and communication of results, with proactive advice and next steps within the local and broader teams
Accountabilities :
Education & Competencies (Technical and Behavioral) :
Takeda Compensation and Benefits Summary
We understand compensation is an important factor as you consider the next step in your career. We are committed to equitable pay for all employees, and we strive to be more transparent with our pay practices.
For Location : Boston, MA
U.S. Base Salary Range :
133,000.00 - $209,000.00
The estimated salary range reflects an anticipated range for this position. The actual base salary offered may depend on a variety of factors, including the qualifications of the individual applicant for the position, years of relevant experience, specific and unique skills, level of education attained, certifications or other professional licenses held, and the location in which the applicant lives and / or from which they will be performing the job.The actual base salary offered will be in accordance with state or local minimum wage requirements for the job location.
U.S. based employees may be eligible for short-term and / or long-termincentives. U.S.based employees may be eligible to participate in medical, dental, vision insurance, a 401(k) plan and company match, short-term and long-term disability coverage, basic life insurance, a tuition reimbursement program, paid volunteer time off, company holidays, and well-being benefits, among others. U.S.based employees are also eligible to receive, per calendar year, up to 80 hours of sick time, and new hires are eligible to accrue up to 120 hours of paid vacation.
EEO Statement
Takeda is proud in its commitment to creating a diverse workforce and providing equal employment opportunities to all employees and applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, gender expression, parental status, national origin, age, disability, citizenship status, genetic information or characteristics, marital status, status as a Vietnam era veteran, special disabled veteran, or other protected veteran in accordance with applicable federal, state and local laws, and any other characteristic protected by law.
Locations Boston, MA
Worker Type Employee
Worker Sub-Type Regular
Time Type Full time
Job Exempt
It is unlawful in Massachusetts to require or administer a lie detector test as a condition of employment or continued employment. An employer who violates this law shall be subject to criminal penalties and civil liability.
Salary : $133,000 - $209,000
