Demo

Senior Director, Biological Modeling

Tempus AI
Seattle, WA Full Time
POSTED ON 2/21/2025
AVAILABLE BEFORE 3/20/2025
Passionate about precision medicine and advancing the healthcare industry?

Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.

Recent technological advances make it possible for AI to impact clinical care. Tempus’ proprietary platform connects an entire ecosystem of real-world evidence to deliver actionable insights to physicians, providing critical information about the right treatments for the right patients at the right time. These insights are also experimentally evaluated in our state of the art Biological Modeling Laboratory to accelerate the development of new therapeutic options for patients. We are seeking a Senior Director to lead the growth of our laboratory team and to scale our operations and novel technology portfolio to further our precision oncology mission.

What You’ll Do

  • Lead a research team of high performing scientists and technicians to increase the throughput of our 3D organoid CRISPR-based target ID screening platform to genome-scale
  • Oversee the development of new methodologies to scale organoid drug screening assays for high throughput evaluation of therapeutic response and mechanism
  • Work with bioinformatics and translational research to streamline a process for generating clinically relevant insights from integrated evaluation of organoid screens and real world data (RWD) sets
  • Drive strategic thinking to create a best-in-class lab-in-the-loop platform to drive the AI era of oncology target ID/validation
  • Engage with commercial and academic strategic partners to create next-gen models representing current unmet needs and indications in oncology
  • Collaborate with engineers, computational biologists, data scientists, and machine learning scientists on R&D initiatives both internally and with our strategic partners in pharma

Qualifications

  • PhD with 10 years laboratory experience and at least 5 years in industry
  • More than five years of experience managing an industrial-scale research laboratory
  • Demonstrated expertise with high throughput assay development, molecular profiling, and tool building
  • Experience with initial laboratory automation builds, associated data pipeline builds, and upgrades
  • Experience with both internal and external projects involving multidisciplinary teams or collaborations

Preferred Candidates Will Possess

  • Track record of developing novel protocols, assays, and onboarding new screening technologies involving 3D cell culture or organoids
  • Majority of industrial experience within a pharmaceutical drug discovery or development setting
  • PhD in quantitative sciences or engineering
  • Experience leading and managing teams
  • Collaborative skills across organizational levels
  • Strategic thinking

We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

Additionally, for remote roles open to individuals in unincorporated Los Angeles – including remote roles- Tempus reasonably believes that criminal history may have a direct, adverse and negative relationship on the following job duties, potentially resulting in the withdrawal of the conditional offer of employment: engaging positively with customers and other employees; accessing confidential information, including intellectual property, trade secrets, and protected health information; and appropriately handling such information in accordance with legal and ethical standards. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law, including the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.

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