Demo

Senior Scientist, Oligonucleotide Chemistry

Tessera Therapeutics
Somerville, MA Full Time
POSTED ON 1/21/2025
AVAILABLE BEFORE 2/19/2025
Your Experience Includes…

  • PhD with 5 years of relevant industry experience.
  • Excellent knowledge and thorough understanding of SPS and purification of Oligo’s
  • Leading design of oligos based on structure guided approach
  • In-depth knowledge of oligo modification strategy
  • Expert in operating instruments and equipment including HPLC, LC-MS, UV/Vis, MerMade, Dr. Oligo, AKTA Oligo Pilot Synthesizers
  • Data analysis and decision making to make recommendations/presentations to senior leadership
  • Prior experience leading direct reports – people/team management experience
  • Ability to work efficiently within a dynamic team and/or independently under aggressive timeliness are required

You are interested in…

  • Driving innovation in oligo synthesis including design, synthesis and characterization of novel oligonucleotide structures to improve potency and efficacy.
  • Cross functional collaboration with research, translational biology, CMC and other groups
  • Managing and mentoring junior scientific staff and leading associates in a cross-functional environment.

About you:

You are a tenured scientist with experience working on oligonucleotide therapeutics in the biotechnology industry. You have managed direct reports in the past and enjoy being a people manager in the lab. You are interested in Oligonucleotide synthesis and design optimization to enable discovery programs. You have experience with small to mid-scale synthesizers and purification, analytical characterization of chemically synthesized oligonucleotides and optimization of the oligonucleotide platform.

Tessera employees are creative and collaborative problem solvers. They have a strong sense of integrity and unwavering commitment to scientific excellence.

Meet your Manager:

All inquiries regarding the posted position should be directed to the Talent Partner (see below). Interested individuals must apply directly to be considered for the opening.

This position reports to: Sandeep Nema – Senior Vice President, Technical Development

Meet our Leadership Team and Board of Directors

Meet your Talent Partner:

Narissa Furtado-Cordeiro - Manager, Talent Acquisition 

Tessera offers a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits currently include group medical, vision and dental coverage, group life and disability insurance, 401(k) with company contribution, tuition reimbursement, and much more.

Company Summary:

Tessera Therapeutics is pioneering Gene Writing™— a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source. Gene Writing holds the potential to become a new category in genetic medicine, building upon recent breakthroughs in gene therapy and gene editing while eliminating important limitations in their reach, utilization, and efficacy. Tessera Therapeutics was founded by Flagship Pioneering, a life sciences innovation enterprise that conceives, resources, and develops first-in-category companies to transform human health and sustainability.

More about Tessera Therapeutics:

Tessera is proud to be an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, national origin, disability status, marital status, genetics, protected veteran status, citizenship status, sexual orientation, gender identity or expression, or any other characteristic identified by federal, state, or local laws where we operate. Tessera provides reasonable accommodations to qualified applicants and employees with disabilities. To begin an interactive dialogue with Tessera regarding a reasonable accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied, please contact the recruiter or Accommodations@tesseratx.com

Recruitment & Staffing Agencies: Tessera Therapeutics does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Tessera Therapeutics or its employees is strictly prohibited unless contacted directly by Tessera Therapeutics’ internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Tessera Therapeutics, and Tessera Therapeutics will not owe any referral or other fees with respect thereto.

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