Demo

Scientist II, Molecular Design

tesseratherapeutics
Somerville, MA Full Time
POSTED ON 4/23/2025
AVAILABLE BEFORE 6/22/2025

Your experience includes… 

  • PhD. in Computational Biology, Biophysics, Biochemistry, Bioengineering, Computational Chemistry, Computer Science, or related discipline
  • 2 years of industry experience applying computational or machine learning methods to model and engineer molecules
  • Strong foundation in computational biophysics and structure-based protein design.
  • Fluency in one or more programming languages, especially Python.
  • Experience in machine learning, especially in applying deep neural network models of protein evolution, structure, or function. 

You are interested in… 

  • Developing and applying molecular modeling and design strategies to advance Tessera's Gene Writing platform.
  • Collaborating closely with experimental scientists to realize molecular designs, collect and analyze data, and build mechanistic intuition and biochemical understanding.
  • Working as part of a multi-disciplinary team alongside ML scientist and engineers to devise, train, refine, and deploy deep neural network models using public and proprietary sequence, structure, and function data.
  • Presenting scientific findings to broad audiences including senior leadership to drive decision making in program teams.
  • It’s a bonus if you have experience in modeling enzymes that interact with nucleic acids

About you: 

You are a talented, creative, and self-motivated Molecular Design Scientist excited to join Tessera’s Data Sciences team. You bring a strong foundation in computational biophysics and structure-based protein design, and you're eager to apply computational modeling and design methods to support the discovery and engineering of novel gene editing technologies. You thrive in a collaborative environment, working closely with both computational and bench scientists to develop and apply protein engineering strategies powered by machine learning and physics-based methods. You are eager to contribute your scientific and technical expertise across a multidisciplinary team—emphasizing conceptualization, experimentation, data analysis, presentation, and strategic planning.

Meet your manager:

Giota Kyriakou - Senior Scientist, Protein Design 

Meet our Leadership Team and Board of Directors 

Meet your Talent Partner:

Narissa Furtado-Cordeiro - Manager, Talent Acquisition

 

Tessera offers a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits currently include group medical, vision and dental coverage, group life and disability insurance, 401(k) with company contribution, tuition reimbursement, and much more.

Company Summary:

Tessera Therapeutics is pioneering Gene Writing™— a new biotechnology designed to offer scientists and clinicians the ability to write small and large therapeutic messages into the genome, thereby curing diseases at their source. Gene Writing holds the potential to become a new category in genetic medicine, building upon recent breakthroughs in gene therapy and gene editing while eliminating important limitations in their reach, utilization, and efficacy. Tessera Therapeutics was founded by Flagship Pioneering, a life sciences innovation enterprise that conceives, resources, and develops first-in-category companies to transform human health and sustainability.

More about Tessera Therapeutics:

Tessera is proud to be an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, age, sex, national origin, disability status, marital status, genetics, protected veteran status, citizenship status, sexual orientation, gender identity or expression, or any other characteristic identified by federal, state, or local laws where we operate. Tessera provides reasonable accommodations to qualified applicants and employees with disabilities. To begin an interactive dialogue with Tessera regarding a reasonable accommodation in connection with the hiring process and/or to perform the essential functions of the position for which the applicant has applied, please contact the recruiter or Accommodations@tesseratx.com

Recruitment & Staffing Agencies:  Tessera Therapeutics does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Tessera Therapeutics or its employees is strictly prohibited unless contacted directly by Tessera Therapeutics’ internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Tessera Therapeutics, and Tessera Therapeutics will not owe any referral or other fees with respect thereto.

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