Demo

Scientist

The Fountain Group
Cambridge, MA Contractor
POSTED ON 2/5/2025
AVAILABLE BEFORE 3/7/2025

Currently I have an opening for a Scientist located in Cambridge, MA. Details for the position are as follows:

Job Description:

  • Design and implement experiments to screen for drug candidates, and to address mechanisms-of-action of therapeutic molecules.
  • Perform complex cell-based functional experiments independently and act as a subject matter expert (SME) for drug discovery in the Cell therapy and Immuno-Oncology/Immuno Therapy.
  • Provide broad assay development support for early-stage drug discovery projects in disease areas of the Cell therapy and Immuno-Oncology/Immuno Therapy
  • Design, execute and validate a variety of assays to understand mechanism of action and characterize different biologics (e.g., mAb, T cell engagers) and cell therapy new modalities (e.g., CAR-T, CAR-NK)
  • Collaborate with automation engineers to identify suitable approaches to utilize laboratory automation for the execution of variable cell-based assays.
  • CAR T/NK generation (transduction and expansion) and functional evaluation of CAR expression, phenotyping, cytokine detection and killing potency in vitro.
  • Spend ~ 85% of time in laboratory to maintain and implement cell-based assay platform and perform experiments.
  • Recent PhD, Masters with 2 , or Bachelors with 5 years of experience in tissue, NK, or T-cell culturing and research focusing on immunology or oncology. Proficiency in immune cell phenotyping (surface/intracellular), cytokine detection (multi-color flow cytometry, Luminex, MSD), cytotoxicity assay and High content imaging (Opera Phenix) or other functional assays.

Technical Information:

  • Pay: $45-51 hourly, depending on experience level
  • Onsite, M-F, 8am-5pm
  • 6-month contract with potential for extension

Salary : $45 - $51

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