Summer Intern

Job title: Metabolomics Research Intern

Company: Theriome Inc.

Job Type: Internship - 35 hours per week for 10 weeks

Compensation: $21.42 per hour

Work Location: In-person (Phoenix, AZ)

Application Deadline: Monday, April 7, 2025, at 5:00 pm MST

About Theriome Inc.

Theriome Inc. is at the forefront of personalized health diagnostics, leveraging advanced metabolomics to decode complex biological systems. Through mass spectrometry-based metabolomic analysis, we empower individuals and healthcare providers with actionable health insights. Our pioneering Aristotle Test and multi-omic research integrate cutting-edge analytical techniques, data science, and scientific rigor to revolutionize precision medicine.

We are seeking a highly motivated and scientifically driven Metabolomics Research Intern to join our research and development team for the summer. This internship will provide hands-on experience in wet lab procedures, computational metabolomics, and scientific writing, with an expectation of contributing to a peer-reviewed publication. 

Key Responsibilities

The Metabolomics Research Intern will be engaged in three primary domains of metabolomics science, requiring both technical proficiency and scientific acumen:

1. Bench-Side Sample Preparation for Mass Spectrometry Analysis

• Perform dried blood spot (DBS) sample processing for gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-tandem mass spectrometry (LC-MS/MS) analysis.
• Execute critical pre-analytical steps, including extraction, derivatization, and sample preparation, adhering to validated laboratory protocols.
• Maintain meticulous laboratory records and ensure high standards of laboratory etiquette and safety.
• Receive specialized training in protocol execution, with an expectation of prior familiarity with laboratory best practices.

1. Computational Analysis of Multi-Omic and Metabolomic Data

• Process, interpret, and analyze high-dimensional metabolomics data derived from mass spectrometry experiments.
• Utilize chemometric techniques to discern biological patterns, metabolite associations, and physiological implications.
• Gain direct mentorship in statistical and computational methodologies, including principal component analysis (PCA), machine learning-based clustering, and pathway enrichment analysis.
• Employ coding languages such as Python, R, or MATLAB to develop and execute analytical workflows—prior coding proficiency is expected.
• Contribute to the preparation of data visualization and bioinformatics reports for publication.

1. Scientific Writing and Manuscript Preparation

• Assist in drafting scientific manuscripts, including the methods, results, and discussion sections, with a focus on metabolomic interpretation.
• Receive structured mentorship in academic writing, literature synthesis, and journal submission processes, with an expectation that the work produced will contribute to a peer-reviewed publication.
• Maintain precise documentation of research findings in alignment with publication standards.

Required Qualifications

• Educational Background: Currently pursuing or recently completed a degree in biochemistry, analytical chemistry, bioinformatics, molecular biology, biomedical engineering, or a related field.
• Laboratory Proficiency: Demonstrated wet lab experience in a research setting, particularly in sample preparation, chromatography, or mass spectrometry techniques.
• Computational Competency: Familiarity with coding languages (Python, R, or MATLAB) for data processing, statistical analysis, or bioinformatics applications.
• Scientific Writing Expertise: Proven ability to write clearly and concisely, with prior experience in manuscript drafting, literature review, or academic publishing.
• Attention to Detail: Strong analytical and organizational skills, with the ability to meticulously document experiments and findings.
• Commitment to Research: A passion for metabolomics, systems biology, and translational research, with a drive to contribute to scientific advancements.

Preferred Qualifications

• Experience in mass spectrometry-based metabolomics or multi-omics data integration.
• Background in chemometric analysis, multivariate statistics, or machine learning applications.
• Previous participation in peer-reviewed research projects, grant-funded initiatives, or bioinformatics workflows.
• Familiarity with scientific visualization tools (ggplot2, Seaborn, or MetaboAnalyst).

Internship Benefits

• Competitive Compensation: $21.42/hour for 35 hours per week over a 10-week period.
• Publication Opportunity: Direct involvement in a manuscript submission to a peer-reviewed journal.
• Mentorship & Training: One-on-one guidance from leading systems biology researchers, including chemometric analysis, bioinformatics workflows, and scientific writing mentorship.
• Hands-on Laboratory Experience: Work with state-of-the-art mass spectrometry instrumentation and real-world biological datasets.
• Professional Development: Gain invaluable experience in translational research, metabolomics data analysis, and publication processes, setting a strong foundation for graduate programs or industry careers.

Application Process

Interested candidates should submit:

1. A current resume detailing relevant experience.
2. A cover letter addressing research interests, laboratory skills, computational experience, and motivation for applying.

Theriome Inc. is committed to scientific excellence, innovation, and equity in research. We encourage applications from diverse backgrounds and individuals who are passionate about pioneering the future of metabolomics and precision medicine.

Compensation

This is a 10-week paid internship (35 hours/week) with an anticipated start date of May 26, 2025. Hourly pay is approximately $21.42/hour.

For this internship, the selected candidate(s) will be hired on as a 1099 employee. If you are an international student, your immigration status may require specific work authorization to be able to work off-campus. 

• If you are an ASU student, please refer to the International Student Scholars Center (ISSC) for more details. 
• If you are an MCCCD student, please contact your International Student Advisor at your college for more details.

For more guidance, please contact your student advisor.

Apply here: https://www.worldlabs.org/group/5ttXQcsqpRwEZiEsg/mkt/internships

Application Deadline: Monday, April 7, 2025 at 5:00 pm MST