What are the responsibilities and job description for the Solid State Scientist III position at Thermo Fisher Scientific?
Work Schedule
Standard (Mon-Fri)Environmental Conditions
Laboratory SettingJob Description
As a Solid-State Scientist III at Thermo Fisher Scientific Inc., you will use your expertise in solid-state characterization and analytical method validation to advance drug substance development. Collaborate with premier teams and ensure our methodologies meet regulatory standards.
Key Responsibilities:
- Perform solid-state characterization of drug substances and products using sophisticated analytical techniques, including X-ray powder diffraction (XRPD), differential scanning calorimetry (DSC), thermogravimetric analysis (TGA), FTIR, particle size analysis, and polarized light microscopy.
- Expertise in investigating critical solid-state properties such as polymorphism, crystallinity, amorphous content, and particle morphology to support pharmaceutical development.
- Develop and validate analytical methods in compliance with regulatory guidelines (e.g., ICH) and analyzing experimental data to prepare comprehensive technical reports, presentations, and regulatory submissions.
- Effective collaboration with formulation development, process development, and quality teams is important for supporting drug development programs.
- Stay with advancements in solid-state characterization technologies and apply innovative ways to improve experimental workflows.
Qualifications:
- PhD or equivalent experience in Pharmaceutical Sciences, Chemistry, Materials Science, or a related field with a focus on solid-state chemistry and/or analytical methods.
- Hands-on experience with solid-state analytical techniques, including XRPD, DSC, TGA, FTIR, Raman spectroscopy, and microscopy (academic or industrial).
- Basic understanding of polymorphism, amorphous systems, crystallinity, and their implications in drug development.
- Experience in method development, validation, and troubleshooting for analytical techniques.
- Strong data analysis and interpretation skills, proficient in software tools such as HIgh Score Plus, Trios, or related programs.
- Excellent interpersonal, problem-solving, and time-management skills.
- Strong written and verbal communication skills to collaborate within cross-functional teams.
Preferred candidates will have prior experience in pharmaceutical solid-state analysis gained through internships, academic research, or industry roles. Familiarity with ICH guidelines and regulatory requirements for method validation and solid-state characterization. Additionally, knowledge of formulation concepts and drug product development processes will be valuable for participating in cross-functional drug development initiatives.
Benefits include: 401K, Health, Vision, and Dental insurance.
