Medical Director

Medical Director 

About the Position:

The Medical Director will provide strategic medical guidance to lead the development of new hematology / oncology agents. Responsible for one or more clinical programs across indications, multiple assets, or a large complex program. Accountable for the design, implementation, and conduct of clinical development program(s) to support decision milestones and regulatory requirements.Treeline has a robust research pipeline from discovery to clinic, and we are working rigorously to leverage this for the greatest possible impact for patients. As a clinician and scientist, you will be bridging the basic research with clinical development strategy in this scientifically rich environment.

Responsibilities:

Clinical Development Planning

• Provides clinical leadership and strategic medical guidance for the development of new agents across the company’s early pipeline
• Responsible for creating clinical development plan(s) that foresee and support subsequent registration trials
• Maintains the highest standards of scientific and clinical knowledge in the specific therapeutic area(s) of assignment.
• Stays informed and up to date of internal and external developments, trends, and other dynamics relevant to the clinical development plan, and maintains a current view of the relevant disease area(s) to inform strategy.
• Liaises with internal stakeholders and outside experts, advisory boards, patient advocacy groups and regulatory authorities and represent assigned programs to those groups and authorities
• May support Business Development and Licensing activities

Clinical Development Implementation

• Collaborates with clinical scientists, clinical operations, scientists and subject matter experts to develop clinical trial protocols
• Provides the clinical and expert input in the development of clinical sections of Investigator Brochures, presentations, and other materials.
• Regularly engages with the relevant external investigators; participate in the identification and selection of appropriate external investigators and sites.
• Applies their medical knowledge to guide the safe, ethical and efficient conduct of the trials under their responsibility
• Maintains compliance with Good Clinical Practice guidelines and Treeline Standard Operating Procedures
• Acts as the medical monitor for assigned studies and conduct ongoing reviews of clinical trial data.
• Collaborates within a multidisciplinary team including biostatisticians, data managers and statistical programmers to develop study analytics and data review plans.
• Collaborates with the Translational Biomarker team to strategize, design, and implement biomarker plans.
• Reviews study data to ensure correct medical/scientific data interpretation for interim and final study reporting.
• Collaborates with Clinical Operations for site selection, feasibility, and query resolution etc.
• Collaborates with relevant team members to support regulatory interactions such as end of phase meetings.

Required Skills, Experience, and Education:

• MD with Board-certification (or equivalent expertise) in a Heme/Onc sub-specialty. Clinical practice experience ≥ 4 years.
• Additional lab-based science training is required; PhD is preferred
• Experience leading complex, global, early phase, oncology clinical programs from the pharma/biotech industry and/or credible experience from an academic medical center
• Experience working with the principles and techniques of data analysis, interpretation, and clinical relevance.
• Excellent communication skills, written and oral
• Strong interpersonal skills
• Thorough knowledge of Good Clinical Practice
• Impeccable personal ethical integrity and a commitment to improving the outcomes for patients

Recruitment fraud statement

Please be aware of recruitment fraud and related job scams, where scammers present themselves as recruiters but are seeking to steal money or personal information. Keep the following in mind to protect yourself:

• Treeline Biosciences will never ask for money from you as part of our recruitment process. Do not provide bank details or pay somebody for the promise of a job at Treeline.
• We do not conduct interviews through Skype or Telegram.
• Our job openings are first posted to treeline.bio/careers. If you locate a listing for a Treeline job on another site, please ensure it is also posted on our careers website.
• You can find more information about job scams at consumer.ftc.gov/articles/job-scams.
• To report job scams, head to ReportFraud.ftc.gov.

Notice to Search Firms/Third-Party Recruitment Agencies (Recruiters)

The Human Resources team manages the recruitment and employment process for Treeline Biosciences. To protect the interests of all parties involved, Treeline Biosciences will only accept resumes from a recruiter if an executed search agreement directed to the particular position or positions is in place at the start of the recruitment effort. Unsolicited resumes sent to Treeline Biosciences from recruiters do not constitute any type of relationship between the recruiter and Treeline Biosciences and do not obligate Treeline Biosciences in any way to pay fees should we hire from those resumes. Recruiters are requested not to contact or present candidates directly to our hiring manager or employees.