What are the responsibilities and job description for the RESEARCHER position at UAB Health System?
Position Summary:
As a Researcher, you will play a key role in driving scientific discovery by independently leading and executing research projects. This professional-level position demands a high degree of expertise and judgement in designing studies, analyzing data, and may involve assistants in publishing findings. You will collaborate with cross-functional teams, manage project timelines, and contribute to grant writing and securing funding for future research. Depending on the research focus, this position may involve research participant contact, research animal contact, and/or specimens.
Position plays a key role in driving scientific discovery by independently leading and executing research projects. Conduct experiments in support of CF research, including isolation and quantification of DNA, transformations, cloning of plasmid vectors, and protein extraction from various tissues (primarily ferrets). Provide technical training to new personnel. This professional-level position demands a high degree of expertise and judgement in designing studies, analyzing data, and may involve assistants in publishing findings. Collaborate with cross-functional teams, manage project timelines, and contribute to grant writing and securing funding for future research.
Key Duties and Responsibilities
- Provides technical support by performing complex research related tasks.
- Conduct experiments including isolation and quantification of DNA, transformations, cloning of plasmid vectors, running PCR and RT-PCR, and performing TOPO clones. DNA, RNA, and protein extraction from various tissues (primarily ferrets) and blood using a kit or manually Purification of DNA, DNA cloning, mutagenesis (CRISPR/Cas9 mutagenesis functional analysis) and sequencing analysis
- Acts as a subject matter expert on research methods and equipment functions.
- Provide technical training to new personnel, including isolation and quantification of DNA, transformations, cloning of plasmid vectors, running PCR, IFA, ELISA and cell culture and so on.
- Performs a variety of tests requiring a high degree of proficiency.
- Conduct additional experiments in primary airway cell culture, cell line culture and maintenance, Histochemical /Immunofluorescence technique; tissue collection, embedding, cryosection, and data analysis.
- Proficiency in various molecular cloning operations including PCR, Real-Time PCR, molecular clone, transfection, SDS-PAGE, Westernblotting, Southern-blotting, etc.
- May also conduct Flow Cytometry for transduction efficiency and airway cell differentiation analysis and Virus production and quantification using the qPCR technique
- Evaluates study results using statistical and multivariate analysis, may involve assistance in publishing findings.
- Perform other duties as assigned
Salary Range: $50,050 - $68,780
Master's degree in a related field OR Bachelor's degree in related field and two (2) years of related experience OR Associate's degree in related field and four (4) years of related experience required or High School diploma or GED and six (6) years of related experience required. Work experience may NOT substitute for education requirement.
UAB is an Equal Employment/Equal Educational Opportunity Institution dedicated to providing equal opportunities and equal access to all individuals regardless of race, color, religion, ethnic or national origin, sex (including pregnancy), genetic information, age, disability, religion, sexual orientation, gender identity, gender expression, and veteran's status. As required by Title IX, UAB prohibits sex discrimination in any education program or activity that it operates. Individuals may report concerns or questions to UAB's Assistant Vice President and Senior Title IX Coordinator. The Title IX notice of nondiscrimination is located at uab.edu/titleix.
Salary : $50,050 - $68,780
