What are the responsibilities and job description for the MSAT Scientist or Associate – Cell Therapy Tech Transfer and GMP Production position at uBriGene Biosciences?
Job Title: MSAT Scientist or Associate – Cell Therapy Tech Transfer and GMP Production Location: Germantown MD Company: uBriGene Biosciences
About Us: uBriGene is a leading CDMO specializing in cell and gene therapy manufacturing. We are committed to delivering high-quality products to support clinical and commercial pipelines in the biotech industry.
We are looking for a highly motivated MSAT scientist/ associate to join our team and play a critical role in cell therapy products, especially CAR-T or TIL production from process transferring run, and GMP operation in a cGMP environment. If you are passionate about cutting-edge biotechnology and thrive in a fast-paced environment, this could be the perfect role for you.
Key Responsibilities:
- · Transfer end-to-end engineered cell therapy manufacturing process including the tumor tissue dissociation, target cell isolation, transduction, expansion, harvest and fill/finish and cryopreservation operation into cGMP clinical production.
- · Perform CAR-T operation using LOVO, Sepax and Wave bioreactor.
- · Able to identify available cutting-edge technologies to drive cell therapy process optimization and scale-up solutions to reduce clinical production cost of goods.
- · Author technical reports, SOPs and GMP batch records for tech transfer and GMP operation.
- · Serve as a process subject matter expert to lead process deviation investigation, impact assessment and author related reports
- · Serve as a process subject matter expert to support cGMP operation and process/manufacturing fit assessment/gap analysis of equipment, facilities and processes.
Qualifications:
- · Job title will be adjusted according to candidate background
- · PhD in cell biology, engineering, molecular biology, pharmaceutical chemistry or a related discipline with 0-1 years wet lab experience (academic or industry) or master’s degree with minimal 1-2 years of industry experience or minimal 2-3 years industry experience for BS
- · Industry experience and strong hands-on skills in cell therapy process development and tech transfer are required. Direct experience in CAR-T/CAR-NK or Tumor-infiltrating lymphocyte (TIL) therapy is strongly preferred.
- · Demonstrated experience and hands-on skills in equipment operation such as LOVO, prodigy, Sepax and CRF etc.
- · Familiar with tumor tissue dissociation, cell isolation, transduction, expansion and cryopreservation operation in PD and cGMP environment
- · GMP operation training for gowning and clean room behavior
- · Experience in cell analytical method development and qualification including flow cytometry, qPCR and cytotoxicity assay is strong plus
- · Organizational, multi-tasking and communication skills
- · Able to collaborate and a good team player
- · Able to work in a fast and dynamic environment
Why uBriGene?
At uBriGene, we offer an innovative and collaborative work environment where you will contribute to the cutting-edge development of cell and gene therapies. We are passionate about fostering professional growth and delivering impactful solutions for our clients.
Salary : $70,000 - $80,000
