What are the responsibilities and job description for the Postdoctoral Researcher/Research Scientist position at University of Cincinnati College of Medicine?
The Department of Cancer Biology at the University of Cincinnati has an opening for a Postdoctoral Fellow/Research Scientist supported by NCI R01 grants to study transcriptional and epigenetic gene regulation in breast cancer metastasis and therapeutic resistance. The Zhang laboratory (https://med.uc.edu/zhanglab) currently focuses on elucidating the role and molecular mechanisms of gene- and tissue-specific transcriptional cofactors and small RNAs in liquid-liquid phase separation (LLPS) and the above processes [Estrogen Receptor and Breast Cancer – Celebrating the 60th Anniversary of the Discovery of ER (1st ed, 2019, Springer Nature), Cell Reports (2021) 34(10):108822, Dev Cell (2021) 56(3):341, Cancer Drug Resist (2022) 5(2): 498, Cancers (2024) 16(23):3992]. We are using a combination of biochemical, molecular, genomic, and mouse genetic (conditional knockout, mutant knockin, and overexpression) approaches. We are also currently developing RNA-based nano-therapeutics to target these cofactors and small RNAs to overcome the therapeutic resistance of human breast cancer.