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Postdoctoral Research Associate- Department of Biological Sciences, Polikanov Lab

University of Illinois Hospital
Chicago, IL Other
POSTED ON 4/25/2025
AVAILABLE BEFORE 6/24/2025
Position Summary
Postdoctoral Research Associate will conduct research in the Polikanov lab and be involved in the determination of high-resolution structures of ribosome functional complexes with various protein translation factors, tRNAs, and antibiotics using macromolecular X-ray crystallography and potentially cryo-EM techniques.

Duties & Responsibilities
  • Perform research relevant to the assigned projects;
  • Act independently in terms of planning, executing, and troubleshooting the experiments;
  • Purify bacterial ribosomes and all additional components necessary for the crystallization experiments, such as recombinant proteins, tRNAs;
  • Collect X-ray diffraction data from the ribosome crystals at the APS Synchrotron and/or collect cryo-EM data at the UChicago cryo-EM facility;
  • Perform structural data analysis;, coordinate, analyze, and document results for publication;
  • Directly participate in writing manuscripts and grants based on the obtained experimental data;
  • Train undergraduate and graduate students in research methods, use of equipment, record keeping, and laboratory database entry;
  • Attend weekly group meetings and journal clubs.
  • Other duties, as assigned
  • Perform other related duties and participate in special projects as assigned.
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