Biologist II (In-vivo bioanalyst)

Duration : 12 months Contract

Job Description :

We are seeking a highly motivated and dedicated Ligand Binding Assay Bioanalyst (Biologist II) to join the Quantitative Translational and ADME Sciences (QTAS) department

The LBA Operations Bioanalytical team at ABC QTAS conducts quantitative bioanalysis assays of large molecule therapeutics like mAb, ADC, fusion protein and bi-specifics for Pharmacokinetic (PK), Pharmacodynamic (PD) and Toxicokinetic (TK) studies using ligand binding assays to support drug discovery and early development efforts.

The main responsibilities of a Biologist II involve pre-clinical sample analysis using a ligand binding assay. Sample and reagent management using electronic tools such as Laboratory Information Management System (rLIMS) and others. Sample preparation and analysis utilizing hybrid manual and automated systems to generate high quality bioanalytical data. Reporting results to project teams which enable Pharmacokinetic and Pharmacodynamic analysis.

Responsibilities :

• Plan and execute experiments based on bioanalytical protocol and in vivo study design.
• Analyze pre-clinical in vivo samples based on operational schedule.
• Qualify ligand binding assay based on bioanalysis protocol, interpret result, and make decision on assay readiness.
• Data archiving in ELN and LIMS.
• Effectively communicate experimental plan and results orally and in writing. Contribute to technical report writing and day-to-day lab operations.
• Sample management and sample data QC in LIMS.
• Write and update experimental protocols and procedures.
• Initiate, design, interpret, troubleshoot operational assay independently and efficiently.

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