Basic Scientist Department of Surgery Levi Lab

The Levi Laboratory is seeking a Scientific Faculty at the assistant, associate or professor level with a PhD. Appointment rank will be commensurate with academic accomplishments and experience.

Once established, the preferred candidate will be expected to compete and secure internal and extramural research funding at the local-regional and national levels. Faculty will also have the opportunity to be a part of the robust graduate programs at UTSW:

https://www.utsouthwestern.edu/education/graduate-school/programs/

The laboratory holds large NIH, CPRIT and DOD awards across a diverse portfolio including musculoskeletal injury, repair and regeneration as well as  muscle fibrosis, lymphatic biology and cancer biology.

The Levi lab’s mission is to improve the lives of people living with skin and musculoskeletal injuries and diseases through rigorous science and compassion. Current projects in the Levi laboratory are related to the molecular biology behind tissue fibrosis and the repair and regeneration process in tendon, muscle, and bone. The laboratory integrates multiomics-based approaches with investigations of musculoskeletal development, homeostasis, repair, and regeneration. The laboratory uses transgenic animal models combined with bioinformatic approaches to understand the cell-cell interactions that occur within the stem cell niche under physiological conditions, and strives to understand how these divergent signaling mechanisms may guide future therapeutic strategies to promote faithful repair of damaged tissue.

The scientist will support ongoing molecular biology bench and animal work within the laboratory related to tendon injury/fibrosis, muscle injury/fibrosis, or bone/tendon/muscle regeneration. The ideal candidate should be highly detail-oriented and have a strong collaborative approach. Training will be provided on many lab techniques, but previous experience working with mice and molecular techniques is highly preferred.

Expectations

·         Routine molecular bench work combined with the use of animal models

o    Animal handling, injections, modified diet maintenance, surgeries, and sample collection

·         Downstream processing

o    Histology, immunofluorescent stain and confocal imaging, flow cytometry, and work with cell cultures and single-cell and bulk RNA sequencing

Experience and Education

·         Ph.D. degree with major coursework in field of assignment and five years of research experience in field of assignment, including at least two years at the level of senior research associate or equivalent or

·         Master's degree with major coursework in field of assignment and seven years of research experience in field of assignment, including at least three years at the level of senior research associate or equivalent or

·         Bachelor's degree with major coursework in field of assignment and nine years of research experience in field of assignment, including at least four years at the level of senior research associate or equivalent

·         Able to utilize a variety of molecular biology techniques, including but not limited to PCR, qPCR, western blotting, RNA/DNA extraction, cloning, CRISPR/Cas9 gene editing, and next-generation sequencing

·         Experience with animal handling, animal breeding, genotyping, and animal surgery

·         Experience with single-cell transcriptomic analyses

·         Experience with histology pipeline from tissue harvest to embedding, sectioning, staining, and confocal microscopy

·         Experience with flow cytometry and mass spectrometry

·         Excellent written and oral communication and organizational skills

·         Able to perform data analysis and interpretation using bioinformatics tools, statistical methods, and relevant software packages

UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community.  As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.

This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information.

Appointment rank will be commensurate with academic accomplishment and experience. Consideration may be given to applicants seeking less than a full-time schedule.

To learn more about the benefits UT Southwestern offers, visit https://www.utsouthwestern.edu/employees/hr-resources/

Salary : $1,000 - $1,000,000