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Computational Biologist III, Hon Lab

UT Southwestern Medical Center
UT Southwestern Medical Center Salary
Dallas, TX Full Time
POSTED ON 1/21/2025
AVAILABLE BEFORE 3/21/2025

WHY UT SOUTHWESTERN?
With over 75 years of excellence in Dallas-Fort Worth, Texas, UT Southwestern is committed to excellence, innovation, teamwork, and compassion. As a world-renowned medical and research center, we strive to provide the best possible care, resources, and benefits for our valued employees. Ranked as the number 1 hospital in Dallas-Fort Worth according to U.S. News & World Report, we invest in you with opportunities for career growth and development to align with your future goals. Our highly competitive benefits package offers healthcare, PTO and paid holidays, on-site childcare, wage, merit increases and so much more. We invite you to be a part of the UT Southwestern team where you'll discover a culture of teamwork, professionalism, and a rewarding career!

JOB SUMMARY
Perform professional work in support of scientific research using technical knowledge of software, software development, networking, and/or hardware in a complex computing environment. Subject matter expert in multiple areas of computing technology, and specific knowledge of molecular biology and genetics. Work collaboratively with Principal Investigator ("PI") to determine the most suitable computational methods and tools to analyze large-scale biological data sets. Prepare reports for presentation or publication. Responsible for assisting PI in meeting the system needs for multiple research projects and/or labs.

A Computational Biology III position is available in the laboratory of Gary Hon (www.honlab.org) in the Cecil H. and Ida Green Center for Reproductive Biology Sciences at UT Southwestern Medical Center. As part of NIH’s Impact of Genomic Variation on Function (IGVF) Consortium, our lab has exciting projects related to understanding how genetic variants contribute to diseases of human development in cardiac, neuronal, and placental systems. This team science initiative by the National Human Genome Research Institute will define modern genomics for the coming decade.

The candidate will play a vital role developing new computational approaches that integrate across multimodal datasets including genome-scale CRISPRi Perturb-Seq screens, saturation Prime Editing screens, and morphological Cell Painting screens. We seek creative and energetic individuals with a keen interest in working on a multidisciplinary team science project at the forefront of modern genomics.  Additionally, the candidate will provide high level computational biology and bioinformatic services to Center PI's and researchers for multiple externally funded grants.

The ideal candidate will have a Ph.D. and have experience in computational sciences leading to the development of a new computational method and its publication in a peer-reviewed journal.

BENEFITS
UT Southwestern is proud to offer a competitive and comprehensive benefits package to eligible employees. Our benefits are designed to support your overall wellbeing, and include:

  • PPO medical plan, available day one at no cost for full-time employee-only coverage
  • 100% coverage for preventive healthcare-no copay
  • Paid Time Off, available day one
  • Retirement Programs through the Teacher Retirement System of Texas (TRS)
  • Paid Parental Leave Benefit
  • Wellness programs
  • Tuition Reimbursement
  • Public Service Loan Forgiveness (PSLF) Qualified Employer
  • Learn more about these and other UTSW employee benefits!



EXPERIENCE AND EDUCATION
Required

  • Education
    PhD In a related field of science or technology or
    Master's Degree In Computer Science or a related field of biological science or
    Bachelor's Degree In Computer Science or a related field of biological science

  • Experience
    4 years Related research experience in bioinformatics and computational biology with PhD. or
    6 years Related research experience in bioinformatics and computational biology with Master's Degree or
    8 years Related research experience in bioinformatics and computational biology with Bachelor's degree.


JOB DUTIES

    • Collaborate with PI to identify and develop new concepts and programs for data collection and analysis. Use expert knowledge to develop new methods and techniques for obtaining solutions.
    • Perform, or direct others to perform, complex data analysis related to specialized research methodologies and results.
    • Manage assigned research projects with minimal input from PI. Direct projects with undefined time lines and uncertain outcomes, requiring analysis from multiple perspectives.
    • Use bioinformatics tools and related laboratory and public databases to support research objectives.
    • Oversee development of software to support new and ongoing research projects.
    • Oversee resolution of hardware, software, and network issues in support of laboratory objectives.
    • Oversee the development and maintenance of complex databases to support new and ongoing research projects.
    • Oversee the training of laboratory staff in the use of pertinent research systems.
    • Prepare research reports for presentation, and assist with preparation of manuscripts for publication.
    • May specialize in bioinformatics, software development, network administration, or hardware/software maintenance.
    • Perform other duties as assigned.


SECURITY AND EEO STATEMENT
Security
This position is security-sensitive and subject to Texas Education Code 51.215, which authorizes UT Southwestern to obtain criminal history record information.

EEO Statement
UT Southwestern Medical Center is committed to an educational and working environment that provides equal opportunity to all members of the University community. As an equal opportunity employer, UT Southwestern prohibits unlawful discrimination, including discrimination on the basis of race, color, religion, national origin, sex, sexual orientation, gender identity, gender expression, age, disability, genetic information, citizenship status, or veteran status.

Salary : $1,000 - $1,000,000

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