Director, IT Compliance & Governance

The Company

Verve is a clinical-stage genetic medicines company established with a mission to solve the global health epidemic of cardiovascular disease. Founded by world-leading experts in cardiovascular medicine, human genetics and gene-editing, Verve is pioneering a new approach to the care of cardiovascular disease, potentially transforming treatment from chronic management to single-course gene editing medicines. The company’s initial three programs – VERVE-101, VERVE-102, and VERVE-201 – target genes that have been extensively validated as targets for lowering low-density lipoprotein cholesterol (LDL-C), a root cause of cardiovascular disease. VERVE-101 and VERVE-102 are designed to permanently turn off the PCSK9 gene in the liver and are being developed initially for heterozygous familial hypercholesterolemia (HeFH) and ultimately to treat atherosclerotic cardiovascular disease (ASCVD) patients not at goal on oral therapy. VERVE-201 is designed to permanently turn off the ANGPTL3 gene in the liver and is initially being developed for homozygous familial hypercholesterolemia (HoFH) and ultimately to treat patients with refractory hypercholesterolemia. In 2024, Verve was named a Top Place to Work by The Boston Globe for the fourth consecutive year. Verve is headquartered in Boston, Massachusetts.

The Position

Verve is seeking an experienced and dynamic Director of IT Compliance and Governance to lead and enhance our compliance programs in a highly regulated environment. This role will drive the design, implementation, and continuous improvement of IT policies, procedures, controls, and data governance frameworks to ensure compliance with SOX, GxP guidelines, data privacy regulations (e.g., GDPR), and other applicable standards. The ideal candidate will safeguard data integrity, ensure regulatory adherence, and align IT operations with business objectives while fostering collaboration across teams and stakeholders, supporting Verve's commitment to quality and accountability.

This is a hybrid role and requires 3-days in our Boston office. We are considering local candidates at this time.

Job Responsibilities

• Lead the design, implementation, continuous improvement and compliance of Information Technology General Controls and Information Technology Access Controls to maintain compliance with SOX requirements ensuring alignment with corporate objectives.
• Identify potential risks, close compliance gaps, and implement effective controls by collaborating with Finance, IT, and HR, turning strategic initiatives into actionable, impactful plans.
• Serve as a key partner to internal and external auditors, ensuring seamless SOX testing and remediation processes while upholding transparency and accountability.
• Collaborate with Quality, R&D, and operational teams to develop IT SOPs, documentation, and training programs that meet GxP regulatory standards, including 21 CFR Part 11, reinforcing operational excellence.
• Design and enforce robust policies and controls that ensure personal data protection and compliance with GDPR, 201 CMR 17.00, and other privacy regulations, demonstrating leadership in data governance.
• Work closely with HR, Legal, Finance, and other departments to weave compliance requirements into everyday practices, enhancing operational integrity and accountability.
• Build and refine data governance frameworks to guarantee security, accuracy, and usability throughout the data lifecycle, ensuring adherence to internal data integrity policies.
• Act as the IT compliance lead during audits, providing expert insights and reinforcing the organization’s commitment to regulatory excellence.
• Other duties as assigned.
  
  

Qualifications

• Education & Experience
• Bachelor’s degree in information technology, computer science, or relevant field.
• At least 10 years of relevant experience in IT compliance, governance, or related roles, preferably in a SOX-regulated biotech or pharmaceutical environment.
• Strong knowledge of SOX compliance, GxP regulations, 21 CFR Part 11, and data privacy laws (e.g., GDPR, 201 CMR 17.00).
• Strong understanding of regulatory frameworks relevant to a clinical stage biotech organization.
• Skills & Abilities
• Proven ability to lead and develop teams, managing complex projects and solving abstract problems.
• Strong communication and negotiation skills, with experience influencing stakeholders and aligning organizational objectives.
• Demonstrated ability to set strategic direction and translate it into actionable plans.
• High emotional intelligence, with skills in conflict resolution and understanding diverse perspectives.
• Experience in budget management and accountability for departmental or cross-functional finances.
• Ability to bring structure to ambiguous situations and develop overarching frameworks for projects.
• Track record of mentoring and developing future leaders within an organization.
  

Don’t check off every box in the requirements listed above? Please consider applying anyway. We want the best candidates for the job, and those candidates don’t always meet 100% of the qualifications listed. At Verve, we are dedicated to building diverse and inclusive teams who embody the values we share: grit, spirit, drive, and passion. We look forward to learning more about your unique background.

EEO Statement

Verve Therapeutics is proud to be an equal opportunity workplace and is an affirmative action employer. We are committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status. If you have a disability or special need that requires accommodation, please let us know.

Recruitment & Staffing Agencies

Verve Therapeutics does not accept agency resumes unless contacted directly by internal Verve Talent Acquisition. Please do not forward resumes to Verve employees or any other company location; Verve Therapeutics is not responsible for any fees related to unsolicited resumes.