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Postdoctoral Researcher, Translational Proteomics

Vividion Therapeutics, Inc
San Diego, CA Full Time
POSTED ON 1/20/2025
AVAILABLE BEFORE 4/13/2025

Job Description

Job Description

Description :

Note : this onsite assignment is estimated to last two years, beginning in early 2025.

Company Overview :

Vividion is a next generation biotechnology company based in San Diego that is leveraging its proprietary chemical proteomics platform to conduct proteome-wide footprinting of drug-protein interactions with unprecedented breadth and precision. Our technology allows us to screen, identify and optimize novel drugs that selectively bind virtually any protein, including proteins previously considered “undruggable”. Our pipeline and emerging programs reflect a matured and productive platform capable of delivering first in class drugs utilizing novel mechanisms of action (allosteric inhibitors, protein-protein interaction inhibitors, functional activators, degraders etc.) against undruggable targets in the oncology and immunology space.

We are uniquely structured with opportunities for all scientists to contribute to both established programs as well as ongoing early target selection, screens and validation. We prize scientific excellence, creativity, team players and we are committed to continued innovation. We have worked hard to create a collaborative and dynamic work culture where your ideas and discoveries are valued and will have an impact. We are growing and there are opportunities for mentorship and career progression.

Vividion was ranked #2 mid-size company on The San Diego Union-Tribune's 2022 and 2023 Top Workplaces list.

Job Summary :

The successful candidate will have extensive hands-on experience with quantitative LC-MS / MS assay development and validation. The position will be responsible for developing and validating fit-for-purpose assays to measure protein biomarkers for future clinical trials and building out workflows to enable FFPE tissue and plasma biomarker discovery and quantification. This position will work closely with our proteomics, translational, and clinical biomarker teams.

Requirements :

Education and Experience requirements :

  • PhD in analytical chemistry or related fields
  • Required technical skills include targeted LC-MS / MS assay development and validation. Experience with Thermo Orbitrap instruments and Skyline are a plus
  • Ability to process different sample types including fresh frozen tissues, FFPE biopsies, tumor biopsies, PBMCs, and / or plasma
  • Experience with proteomics is a plus

Required Key Attributes :

  • Excellent organization and communication skills; ability to prioritize tasks and manage time effectively; attention to detail and good documentation habits
  • Candidates must have effective troubleshooting and problem-solving skills
  • Candidates must be a team player and strong individual contributor, flexible, and able to handle multiple tasks and deliver high quality results under tight timelines
  • Pay & Benefits :

    The expected compensation for this position is between $80,000 to $90,000 per year commensurate with experience.

    EEO & Employment Eligibility :

    Vividion Therapeutics, Inc. is an Equal Opportunity employer and will consider all qualified applicants for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, or disability status.

    Privacy Policy :

    The protection of your personal information is a commitment we take seriously. For information regarding our Privacy Policy (CA candidates) please visit https : / / vividion.com / publication / privacy - noticeforcalifornia -candidates / .

    Salary : $80,000 - $90,000

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